Kerebel B, Kerebel L M
Oral Surg Oral Med Oral Pathol. 1985 Apr;59(4):371-8. doi: 10.1016/0030-4220(85)90062-3.
Ghost cells in complex odontoma were studied by light microscopic and scanning electron microscopic examination of decalcified sections. They were found at different locations in odontomas: next to tubular dentin, at the site where enamel would be expected; adjacent to remnants of enamel matrix or surrounded by enamel matrix; within granular calcified masses in contact with bone or tubular dentin; in contact with ameloblasts or adjacent to small rests of odontogenic epithelium. They were either isolated or arranged in groups. Their cytoplasm presented a fibrillar component and a lack of keratohyaline. In a complex odontoma, ghost cell keratinization occurs as a result of metaplastic transformation. The calcifying process in these cells was found to be a passive one, with the cells becoming gradually entrapped within the calcified material--bone, osteoid, dentin, dystrophic osteodentin, or dystrophic granular or lamellar types of calcification. Complex odontomas contain both normal and metaplastic odontogenic epithelial cells, which may have lost their developmental and inductive properties.
通过对脱钙切片进行光学显微镜和扫描电子显微镜检查，对复合性牙瘤中的影细胞进行了研究。它们在牙瘤的不同位置被发现：紧邻管状牙本质，在预期釉质所在的部位；与釉质基质残余相邻或被釉质基质包围；在与骨或管状牙本质接触的颗粒状钙化团块内；与成釉细胞接触或紧邻牙源性上皮小残余体。它们要么孤立存在，要么成群排列。其细胞质呈现出纤维成分且缺乏透明角质颗粒。在复合性牙瘤中，影细胞角化是化生转化的结果。发现这些细胞中的钙化过程是一个被动过程，细胞逐渐被困在钙化物质——骨、类骨质、牙本质、营养不良性骨牙本质或营养不良性颗粒状或板层状钙化类型中。复合性牙瘤包含正常和化生的牙源性上皮细胞，这些细胞可能已经失去了它们的发育和诱导特性。
