Suppr超能文献

自闭症儿童在牙科治疗期间的唾液皮质醇水平及其对行为的影响。

Salivary Cortisol Levels and its Implication on Behavior In Children with Autism during Dental Treatment.

作者信息

Abdulla A M, Hegde A M

机构信息

Department of Pedodontics and Preventive Dentistry, A.B Shetty Memorial Institute of Dental Sciences, Nitte University, Mangalore,Karnataka,India.

出版信息

J Clin Pediatr Dent. 2015 Winter;39(2):128-32. doi: 10.17796/jcpd.39.2.f6h32r2531841637.

Abstract

UNLABELLED

The aim of the study was to estimate the diurnal variations of salivary cortisol in children with autism and healthy children and it's implication on behavior during non-invasive dental procedures.

STUDY DESIGN

50 children with autism and 50 healthy children in the age group between 6 to 12 years of both genders with the need for dental treatment were included in the study. Whole unstimulated saliva was collected from them during early hours of the day and during evenings for 2 consecutive days . The collected saliva was then subjected to electrochemiluminescence assay . Minimum invasive dental procedures like hand scaling, pit and fissure sealants and glass ionomer cement restorations were performed for the participants each time after the saliva sample collection and their behavior during the procedures was rated using Frankl's Behavior Rating Scale.

RESULTS

Significant correlation was seen between cortisol levels and behavior in children with autism. As cortisol levels increased in children with autism, behavior worsened and as the cortisol levels decreased they showed positive behaviour.

CONCLUSION

Cortisol acts as a stress marker and studying the diurnal variations of salivary cortisol can help us in attaining better knowledge about the behavior pattern and thereby assist us in modifying the behavior modification procedures and treatment planning in this group of special children.

摘要

未标记

本研究的目的是评估自闭症儿童和健康儿童唾液皮质醇的昼夜变化及其对非侵入性牙科治疗期间行为的影响。

研究设计

本研究纳入了50名自闭症儿童和50名年龄在6至12岁、有牙科治疗需求的健康儿童,男女不限。在连续两天的清晨和傍晚采集他们的全唾液。然后对采集的唾液进行电化学发光测定。每次采集唾液样本后,为参与者进行诸如手工洁治、窝沟封闭和玻璃离子水门汀修复等微创牙科治疗,并使用弗兰克尔行为评定量表对他们在治疗过程中的行为进行评分。

结果

自闭症儿童的皮质醇水平与行为之间存在显著相关性。随着自闭症儿童皮质醇水平的升高,行为恶化;随着皮质醇水平的降低,他们表现出积极行为。

结论

皮质醇作为一种应激标志物,研究唾液皮质醇的昼夜变化有助于我们更好地了解行为模式,从而帮助我们调整这组特殊儿童的行为矫正程序和治疗计划。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验