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[肺癌诊断与治疗管理中的病理采样技术与策略]

[Techniques and strategy of pathological sampling in the diagnostic and therapeutic management of lung cancer].

作者信息

Remmelink M, Sokolow Y, Leduc D

机构信息

Service de pneumologie, chirurgie thoracique et d'anatomopathologie, hôpital universitaire Érasme, 1070 Bruxelles, Belgique.

Service de pneumologie, chirurgie thoracique et d'anatomopathologie, hôpital universitaire Érasme, 1070 Bruxelles, Belgique.

出版信息

Rev Mal Respir. 2015 Apr;32(4):381-93. doi: 10.1016/j.rmr.2014.12.007. Epub 2015 Mar 29.

DOI:10.1016/j.rmr.2014.12.007
PMID:25823934
Abstract

Histopathology is key to the diagnosis and staging of lung cancer. This analysis requires tissue sampling from primary and/or metastatic lesions. The choice of sampling technique is intended to optimize diagnostic yield while avoiding unnecessarily invasive procedures. Recent developments in targeted therapy require increasingly precise histological and molecular characterization of the tumor. Therefore, pathologists must be economical with tissue samples to ensure that they have the opportunity to perform all the analyses required. More than ever, good communication between clinician, endoscopist or surgeon, and pathologist is essential. This is necessary to ensure that all participants in the process of lung cancer diagnosis collaborate to ensure that the appropriate number and type of biopsies are performed with the appropriate tissue sampling treatment. This will allow performance of all the necessary analyses leading to a more precise characterization of the tumor, and thus the optimal treatment for patients with lung cancer.

摘要

组织病理学是肺癌诊断和分期的关键。这种分析需要从原发性和/或转移性病变中获取组织样本。采样技术的选择旨在优化诊断结果,同时避免不必要的侵入性操作。靶向治疗的最新进展要求对肿瘤进行越来越精确的组织学和分子特征分析。因此,病理学家必须合理使用组织样本,以确保有机会进行所有所需的分析。临床医生、内镜医师或外科医生与病理学家之间的良好沟通比以往任何时候都更加重要。这对于确保肺癌诊断过程中的所有参与者协作,以确保通过适当的组织采样处理进行适当数量和类型的活检是必要的。这将能够进行所有必要的分析,从而更精确地描述肿瘤特征,进而为肺癌患者提供最佳治疗。

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Rev Mal Respir. 2015 Apr;32(4):381-93. doi: 10.1016/j.rmr.2014.12.007. Epub 2015 Mar 29.
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