IgG4相关性疾病的脑部受累情况。
Cerebral involvement in IgG4-related disease.
作者信息
Joshi Deepak, Jager Rolf, Hurel Steven, Pereira Stephen P, Johnson Gavin J, Chapman Michael, Fowler Robert, Winstanley Alison, Losseff Nicholas, Webster George Jm
机构信息
Department of Gastroenterology, University College London Hospitals, London, UK;
Department of Radiology, University College London Hospitals, London, UK;
出版信息
Clin Med (Lond). 2015 Apr;15(2):130-4. doi: 10.7861/clinmedicine.15-2-130.
Abstract
IgG4-related disease is a recently recognised multi-system disease. Common organ involvement includes the pancreas, biliary tree and salivary glands. Central nervous system involvement has been infrequently reported. In a single-centre cohort of 84 patients, we report cerebral involvement in three (4%) patients. Details of cerebral involvement in these patients are outlined, including pituitary involvement in two patients and a diffuse autoimmune-like encephalopathy in the other.
摘要
IgG4相关性疾病是一种最近才被认识的多系统疾病。常见的器官受累包括胰腺、胆管树和唾液腺。中枢神经系统受累的报道较少。在一个由84名患者组成的单中心队列中，我们报告了3名（4%）患者出现脑部受累。概述了这些患者脑部受累的详细情况，包括2名患者出现垂体受累，另1名患者出现弥漫性自身免疫样脑病。
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