Bashir Muhammad Naeem, Malik Muhammad Akram
Department of Statistics, Government Municipal College, Faisalabad, Pakistan E-mail :
Asian Pac J Cancer Prev. 2015;16(6):2375-8. doi: 10.7314/apjcp.2015.16.6.2375.
The effects of diet on epidemiology of prostate cancer are inconclusive. Therefore a hospital- based, case-control study was conducted in a rural population of Faisalabad, Pakistan, to examine the impact of dietary factors on risk of cancer development.
This study was based on 102 confirmed cases of prostate cancer and 204 normal controls. Logistic regression was used to estimate odds ratios and 95% confidence intervals for odds ratios to evaluate the relationship between prostate cancer and diet.
Consumption of red meat and fat items significantly increased the prostate cancer risk having odds ratios and 95% confidence intervals of 3.41; 1.46-7.96 and 2.45; 1.17-5.15, respectively. On the other hand, more consumption of vegetables, fluid intake and fruit significantly decreased the prostate cancer risk (odd ratios and corresponding 95% confidence intervals of 0.21; 0.10-0.44, 0.10; 0.05- 0.19 and 0.09; 0.03- 0.23, respectively.
The present study supports the hypothesis that frequent consumption of red meat and fat items may increase prostate cancer risk while more intake of fruit, vegetables and fluid intake may protect against prostate cancer in the relatively low risk group in rural Pakistan.
饮食对前列腺癌流行病学的影响尚无定论。因此，在巴基斯坦费萨拉巴德的农村人口中开展了一项基于医院的病例对照研究，以探讨饮食因素对癌症发生风险的影响。
本研究基于102例确诊的前列腺癌病例和204例正常对照。采用逻辑回归分析来估计比值比及比值比的95%置信区间，以评估前列腺癌与饮食之间的关系。
食用红肉和高脂肪食物显著增加前列腺癌风险，其比值比及95%置信区间分别为3.41（1.46 - 7.96）和2.45（1.17 - 5.15）。另一方面，更多地食用蔬菜、增加液体摄入量和摄入水果显著降低了前列腺癌风险（比值比及相应的95%置信区间分别为0.21（0.10 - 0.44）、0.10（0.05 - 0.19）和0.09（0.03 - 0.23）。
本研究支持以下假设：在巴基斯坦农村相对低风险人群中，经常食用红肉和高脂肪食物可能增加前列腺癌风险，而更多地摄入水果、蔬菜和增加液体摄入量可能预防前列腺癌。
