Grochmal Joey, Midha Rajiv
Cells Tissues Organs. 2014;200(1):13-22. doi: 10.1159/000369450. Epub 2015 Mar 21.
A major advance in the field of peripheral nerve repair has been the advent of stem and progenitor cell use to supplement the regenerative environment in animal models of nerve injury. As Schwann cell replacements, stem cells may be even better suited to promoting regeneration in these scenarios. We review the recent literature detailing the search for the definitive Schwann cell replacement cell, including a look at genetic modification of transplanted cells for nerve injury repair.
外周神经修复领域的一项重大进展是在神经损伤动物模型中使用干细胞和祖细胞来补充再生环境。作为雪旺细胞替代物，干细胞可能更适合在这些情况下促进再生。我们回顾了最近的文献，详细介绍了寻找确定的雪旺细胞替代细胞的研究，包括对用于神经损伤修复的移植细胞进行基因改造的研究。
