Truter Ilse, Shankar Sushma, Bennie Marion, Woerkom Menno van, Godman Brian
Drug Utilization Research Unit (DURU), Department of Pharmacy, Nelson Mandela Metropolitan University, Port Elizabeth 6031, South Africa.
J Comp Eff Res. 2015 Mar;4(2):123-31. doi: 10.2217/cer.14.70.
There have been multiple reforms in South Africa to conserve resources including policies to enhance generic use, such as compulsory generic substitution and copayments. However, there are concerns with the limited knowledge of their impact.
The objective was to determine utilization and expenditure of different proton pump inhibitors (PPIs).
A retrospective drug utilization study was conducted on a prescription database of a medical aid administrator in 2010.
The limited prescribing of single-sourced PPIs accounted for 21.5% of total prescriptions. The limited use of originators omeprazole and lansoprazole accounted for 1.8 and 1.4% of total prescriptions for the molecule, respectively. Generic prices accounted for 36-68% of the originator in 2010. Patients received on average 2.91 PPI prescriptions during the year.
Policies to enhance prescribing of generics appear working. Opportunities exist to further lower generic prices given low prices in some European countries.
南非已进行了多项资源保护改革，包括加强仿制药使用的政策，如强制仿制药替代和共付费用。然而，人们对这些政策的影响了解有限。
目的是确定不同质子泵抑制剂（PPI）的使用情况和支出。
2010年对一家医疗救助管理机构的处方数据库进行了回顾性药物使用研究。
单源PPI的处方量有限，占总处方量的21.5%。原研药奥美拉唑和兰索拉唑的使用量有限，分别占该分子总处方量的1.8%和1.4%。2010年仿制药价格占原研药价格的36 - 68%。患者当年平均接受2.91份PPI处方。
加强仿制药处方的政策似乎正在发挥作用。鉴于一些欧洲国家仿制药价格较低，仍有进一步降低仿制药价格的空间。
