Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Endocrinol Metab (Seoul). 2015 Mar 27;30(1):1-6. doi: 10.3803/EnM.2015.30.1.1.
Recent surge of thyroid cancer, especially papillary thyroid carcinoma (PTC), ignited a debate on over-diagnosis of cancer. Such increase in incidence is a worldwide phenomenon, but it has been the most prominent in Korea. Although increased detection might have played a major role, some evidences suggest that true increase in incidence have also contributed to such phenomenon. PTC is a very common disease being the most common cancer in human. As the mortality due to PTC is relatively low, understanding pathophysiology of the disease and risk prediction in individual patient have particular importance for optimal management, but little has been known. I suggest a reason for such a commonality of PTC, and would like to describe my view on some aspects of PTC including unresolved issue on management based on our recent observations.
近年来甲状腺癌（尤其是甲状腺乳头状癌，PTC）发病率的上升引发了关于癌症过度诊断的争论。这种发病率的上升是一种全球现象，但在韩国最为明显。尽管检出率的增加可能是主要原因，但一些证据表明，发病率的真正上升也促成了这种现象。PTC 是一种非常常见的疾病，是人类最常见的癌症。由于 PTC 的死亡率相对较低，因此了解疾病的病理生理学和个体患者的风险预测对于最佳管理具有特别重要的意义，但目前所知甚少。我提出了 PTC 如此普遍的一个原因，并希望根据我们最近的观察结果，描述我对 PTC 某些方面的看法，包括管理方面尚未解决的问题。
