Mols P, Huynh C H, Dechamps P, Naeije N, Guillaume M, Ham H
Service of Internal Medicine and of Radio-Isotopes, Saint-Pierre University Hospital, Brussels, Belgium.
Chest. 1989 Dec;96(6):1280-4. doi: 10.1378/chest.96.6.1280.
Pulmonary arterial hypertension represents an important parameter for the assessment of the severity of chronic bronchitis. The measurement of the pulmonary arterial pressure, however, requires invasive techniques of limited routine use because of costs and associated risks. The aim of this study is to evaluate whether the 81mKr right ventricular ejection fraction and parameters derived from equilibrium 99mTc red blood cells' right ventricular curve allow a better estimation of PAP than the 99mTc RVEF. In 41 patients with severe chronic bronchitis, the linear correlation between PAP and 99mTc RVEF was -0.61 (p less than 0.001). None of the parameters derived from the right ventricular curve was better correlated to PAP than the 99mTc RVEF. In 16 other chronic bronchitis patients, the 81mKr RVEF correlated moderately to PAP. In conclusion, the alternative isotopic methods proposed in this work do not provide a reliable estimation of pulmonary arterial pressure in patients with chronic bronchitis.
肺动脉高压是评估慢性支气管炎严重程度的一个重要参数。然而，由于成本和相关风险，肺动脉压力的测量需要有限常规使用的侵入性技术。本研究的目的是评估81mKr右心室射血分数和从平衡99mTc红细胞右心室曲线得出的参数是否比99mTc RVEF能更好地估计肺动脉压（PAP）。在41例严重慢性支气管炎患者中，PAP与99mTc RVEF之间的线性相关性为-0.61（p小于0.001）。从右心室曲线得出的参数与PAP的相关性均不如99mTc RVEF。在另外16例慢性支气管炎患者中，81mKr RVEF与PAP呈中度相关。总之，本研究中提出的替代同位素方法不能可靠地估计慢性支气管炎患者的肺动脉压。
