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在口腔念珠菌病存在的情况下,支气管镜检查期间局部利多卡因的快速黏膜吸收。

Rapid mucosal absorption of topical lidocaine during bronchoscopy in the presence of oral candidiasis.

作者信息

Ameer B, Burlingame M B, Harman E M

机构信息

Department of Pharmacy Practice, University of Florida, Gainesville.

出版信息

Chest. 1989 Dec;96(6):1438-9. doi: 10.1378/chest.96.6.1438.

DOI:10.1378/chest.96.6.1438
PMID:2582861
Abstract

Local anesthetic agents are topically applied during diagnostic procedures such as bronchoscopy. These routine procedures are associated with only rare reports of drug toxicity or extensive systemic drug absorption. We report a case of rapid systemic absorption and elevated plasma lidocaine concentrations following a fiberoptic bronchoscopy procedure in a man with oral candidiasis and lung cancer.

摘要

在诸如支气管镜检查等诊断程序中会局部应用麻醉剂。这些常规程序仅有罕见的药物毒性或广泛全身药物吸收的报告。我们报告了一例患有口腔念珠菌病和肺癌的男性在进行纤维支气管镜检查后出现快速全身吸收和血浆利多卡因浓度升高的病例。

相似文献

1
Rapid mucosal absorption of topical lidocaine during bronchoscopy in the presence of oral candidiasis.在口腔念珠菌病存在的情况下,支气管镜检查期间局部利多卡因的快速黏膜吸收。
Chest. 1989 Dec;96(6):1438-9. doi: 10.1378/chest.96.6.1438.
2
Systemic absorption of topical lidocaine in elderly and young adults undergoing bronchoscopy.接受支气管镜检查的老年人和年轻人局部用利多卡因的全身吸收情况。
Pharmacotherapy. 1989;9(2):74-81. doi: 10.1002/j.1875-9114.1989.tb04106.x.
3
Lidocaine blood concentrations during fiberoptic bronchoscopy.
Am Rev Respir Dis. 1975 Jul;112(1):53-7. doi: 10.1164/arrd.1975.112.1.53.
4
[Serum levels of lidocaine as affected by high frequency jet ventilation during bronchoscopies under local anesthesia].[局部麻醉下支气管镜检查期间高频喷射通气对利多卡因血清水平的影响]
Anaesthesist. 1988 Jul;37(7):420-4.
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Plasma concentrations of lignocaine during fibreoptic bronchoscopy.纤维支气管镜检查期间利多卡因的血浆浓度。
Thorax. 1982 Jan;37(1):68-71. doi: 10.1136/thx.37.1.68.
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Systemic absorption of lidocaine after topical application for the treatment of oral mucositis in bone marrow transplantation patients.骨髓移植患者局部应用利多卡因治疗口腔黏膜炎后的全身吸收情况。
J Oral Pathol Med. 1999 Apr;28(4):170-2. doi: 10.1111/j.1600-0714.1999.tb02018.x.
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Reduced systemic absorption of intrabronchial lidocaine by high-frequency nebulization.
J Clin Pharmacol. 1990 Sep;30(9):795-7. doi: 10.1002/j.1552-4604.1990.tb01875.x.
8
Patient comfort and plasma lignocaine concentrations during fibreoptic bronchoscopy.纤维支气管镜检查期间的患者舒适度和血浆利多卡因浓度
Anaesth Intensive Care. 1985 Nov;13(4):370-4. doi: 10.1177/0310057X8501300406.
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The effect of atropine on the oral absorption of lidocaine in man.阿托品对人体利多卡因口服吸收的影响。
Eur J Clin Pharmacol. 1974 Aug 23;7(5):397-400. doi: 10.1007/BF00558214.
10
Pharmacokinetics of EMLA cream 5% application to oral mucosa.5%复方利多卡因乳膏用于口腔黏膜的药代动力学。
Anesth Prog. 1997 Winter;44(1):32-7.

引用本文的文献

1
Influence of Pharyngeal Anaesthesia on Post-Bronchoscopic Coughing: A Prospective, Single Blinded, Multicentre Trial.咽部麻醉对支气管镜检查后咳嗽的影响:一项前瞻性、单盲、多中心试验。
J Clin Med. 2021 Oct 18;10(20):4773. doi: 10.3390/jcm10204773.
2
Lidocaine not so innocent: Cardiotoxicity after topical anaesthesia for bronchoscopy.利多卡因并非无害:支气管镜检查局部麻醉后的心脏毒性。
Indian J Anaesth. 2012 Jan;56(1):95-6. doi: 10.4103/0019-5049.93362.