Department of Biology, University of Konstanz, Konstanz, Germany; Zukunftskolleg, University of Konstanz, Konstanz, Germany.
Department of Biology, University of Konstanz, Konstanz, Germany.
Curr Biol. 2015 Mar 30;25(7):R285-8. doi: 10.1016/j.cub.2015.02.051.
Recently evolved enhancers dominate mammalian gene regulatory landscapes. Mostly exapted from ancestral DNA sequences, many are linked to genes under positive selection. Just as RNA-seq some years ago, unbiased enhancer mapping is on the verge of changing evolutionary research.
最近进化而来的增强子主导了哺乳动物的基因调控景观。它们大多是从祖先 DNA 序列中衍生出来的，许多与受到正选择的基因有关。就像几年前的 RNA-seq 一样，无偏倚的增强子作图即将改变进化研究。
