Ruan C C
Zhonghua Yu Fang Yi Xue Za Zhi. 1989 May;23(3):160-2.
Six natural foods were tested with Ames Test for their anti-mutagenic effect on 2-AF, AFTB, MNNG, NaN3 induced mutagenic activity in TA99 and TA100. The tested substances were extracted repeatedly with acetone. The revertants induced by 2-AF AFTB1 (with TA98, TA100). MNNG (with TA100) were significantly decreased when the six natural foods were added to the medium. The results revealed that all six natural foods showed remarkable inhibitory effect on 2-AF, AFTB1, MNNG induced mutagenic activity for strains TA98 and TA100 and suggested the presence of anti-mutagenic substances in the six natural foods. This experiment provides a scientific basis to the study of food substances for the prevention of carcinogenesis. It is considered that the six natural foods possess remarkable anti-mutagenic effect and is practically valuable in the field of chemoprophylaxis of Cancer in men.
用艾姆斯试验对六种天然食品进行测试，以检测它们对2-氨基芴（2-AF）、黄曲霉毒素B1（AFTB）、N-甲基-N'-硝基-N-亚硝基胍（MNNG）、叠氮化钠（NaN3）在TA99和TA100中诱导的诱变活性的抗诱变作用。受试物质用丙酮反复萃取。当向培养基中添加这六种天然食品时，由2-AF、黄曲霉毒素B1（与TA98、TA100一起）、MNNG（与TA100一起）诱导的回复突变菌落数显著减少。结果表明，所有六种天然食品对TA98和TA100菌株的2-AF、黄曲霉毒素B1、MNNG诱导的诱变活性均表现出显著的抑制作用，并表明这六种天然食品中存在抗诱变物质。本实验为研究预防癌症的食品物质提供了科学依据。据认为，这六种天然食品具有显著的抗诱变作用，在男性癌症化学预防领域具有实际价值。
