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超越果蝇:非果蝇节肢动物群体基因组学的进展

Beyond fruit-flies: population genomic advances in non-Drosophila arthropods.

作者信息

Hasselmann Martin, Ferretti Luca, Zayed Amro

出版信息

Brief Funct Genomics. 2015 Nov;14(6):424-31. doi: 10.1093/bfgp/elv010. Epub 2015 Mar 30.

Abstract

Understanding the evolutionary processes driving the adaptive differentiation of populations is of broad interest in biology. Genome-wide nucleotide polymorphisms provide the basis for population genetic studies powered by advances in high-throughput sequencing technologies. These advances have led to an extension of genome projects to a variety of non-genetic model organisms, broadening our view on the evolution of gene families and taxonomic-restricted novelties. Here, we review the progress of genome projects in non-Drosophila arthropods, focusing on advances in the analysis of large-scale polymorphism data and functional genomics and examples of population genomic studies.

摘要

了解驱动种群适应性分化的进化过程是生物学领域广泛关注的问题。全基因组核苷酸多态性为基于高通量测序技术进展的群体遗传学研究提供了基础。这些进展使得基因组计划扩展到了各种非遗传模式生物,拓宽了我们对基因家族进化和分类学限制的新特性的认识。在此,我们回顾非果蝇节肢动物基因组计划的进展,重点关注大规模多态性数据和功能基因组学分析的进展以及群体基因组学研究的实例。

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