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软骨发育不全与肢体延长:英国队列研究结果及文献综述

Achondroplasia and limb lengthening: Results in a UK cohort and review of the literature.

作者信息

Donaldson James, Aftab Syed, Bradish Christopher

机构信息

Great Ormond Street Hospital for Children, London, UK.

出版信息

J Orthop. 2015 Jan 28;12(1):31-4. doi: 10.1016/j.jor.2015.01.001. eCollection 2015 Mar.

DOI:10.1016/j.jor.2015.01.001
PMID:25829758
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4353991/
Abstract

AIMS

We aim to review the results, complications and outcomes of a single surgeon's series of lower limb lengthening in patients with achondroplasia.

METHODS

Ten achondroplastic children underwent limb lengthening. The patients, medical records and radiographs were reviewed.

RESULTS

The average age at the time of the index operation was 7.8 years. A single surgeon undertook all procedures. The average total length gain was 20.5 cm. The commonest complication was a fractured femur after removal of the frame.

CONCLUSION

Although complication rates were high (70%), none were left with any long-term sequelae and all were pleased with the results.

摘要

目的

我们旨在回顾一位外科医生对软骨发育不全患者进行的一系列下肢延长手术的结果、并发症及结局。

方法

十名软骨发育不全儿童接受了肢体延长手术。对患者、病历及X光片进行了回顾。

结果

初次手术时的平均年龄为7.8岁。所有手术均由同一位外科医生进行。平均总长度增加了20.5厘米。最常见的并发症是拆除固定架后股骨骨折。

结论

尽管并发症发生率较高(70%),但无一例留下任何长期后遗症,且所有人对结果都很满意。

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本文引用的文献

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Growth disturbance after lengthening of the lower limb and quantitative assessment of physeal closure in skeletally immature patients with achondroplasia.软骨发育不全骨骼未成熟患者下肢延长后的生长障碍及骨骺闭合的定量评估。
J Bone Joint Surg Br. 2012 Apr;94(4):556-63. doi: 10.1302/0301-620X.94B4.28375.
2
Is bilateral lower limb lengthening appropriate for achondroplasia?: midterm analysis of the complications and quality of life.成骨不全症患者行双下肢延长术是否合适?:并发症和生活质量的中期分析。
Clin Orthop Relat Res. 2012 Feb;470(2):616-21. doi: 10.1007/s11999-011-1983-y. Epub 2011 Jul 22.
3
Femoral lengthening in achondroplasia: magnitude of lengthening in relation to patterns of callus, stiffness of adjacent joints and fracture.软骨发育不全中的股骨延长:延长幅度与骨痂模式、相邻关节僵硬程度及骨折的关系
J Bone Joint Surg Br. 2009 Dec;91(12):1612-7. doi: 10.1302/0301-620X.91B12.22418.
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Bifocal tibial corrective osteotomy with lengthening in achondroplasia: an analysis of results and complications.双焦点胫骨矫正截骨术联合延长术治疗软骨发育不全:结果与并发症分析
J Pediatr Orthop. 2006 Nov-Dec;26(6):788-93. doi: 10.1097/01.bpo.0000242429.83866.97.
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Response of the physis to leg lengthening.
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J Pediatr Orthop B. 2001 Jul;10(3):238-47.
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Attempted limb lengthenings beyond twenty percent of the initial bone length: results and complications.肢体延长超过初始骨长度的20%:结果与并发症
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Distraction osteogenesis for lengthening of the tibia in patients who have limb-length discrepancy or short stature.肢体长度不等或身材矮小患者胫骨延长的牵张成骨术。
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Prenatal evaluation of fetal anomalies.胎儿异常的产前评估。
Pediatr Clin North Am. 1997 Jun;44(3):537-53. doi: 10.1016/s0031-3955(05)70492-2.