超声引导下近距离间质治疗卵巢癌腹壁转移的病例报告
A case report of ultrasound-guided interstitial brachytherapy for abdominal wall metastases of ovarian cancer.
作者信息
Shi Dan, Wu Ning, Zhao Hongfu, He Mingyuan, Han Dongmei, Cheng Guanghui
机构信息
Department of Radiation Oncology, China-Japan Union Hospital of Jilin University, Changchun, China ; These two authors contributed equally to this work.
Department of Radiation Oncology, China-Japan Union Hospital of Jilin University, Changchun, China.
出版信息
J Contemp Brachytherapy. 2015 Feb;7(1):81-5. doi: 10.5114/jcb.2015.48574. Epub 2015 Jan 26.
PURPOSE
To report the treatment effect of interstitial brachytherapy for abdominal wall metastases of ovarian cancer.
MATERIAL AND METHODS
The patient is a 44-year-old female with a diagnosis of stage IA ovarian cancer. After surgery and two cycles of chemotherapy with paclitaxel and carboplatin, the patient noticed dull pain in the lower abdomen and found a mass located in the subcutaneous tissue, below the operative incision. A diagnostic biopsy showed abdominal wall metastases. After external radiotherapy with a dose of 39.6 Gy in 22 fractions, the residual tumor was treated with interstitial brachytherapy under ultrasound guidance. The brachytherapy dose was 18 Gy in 6 fractions of 3 Gy each.
RESULTS
After 3 weeks of brachytherapy, the tumor had disappeared completely. Interstitial brachytherapy was feasible.
CONCLUSIONS
Interstitial brachytherapy may be a proposed treatment strategy for inoperable superficial metastases, especially for low radiosensitivity cancer.
目的
报告间质近距离放射治疗卵巢癌腹壁转移瘤的治疗效果。
材料与方法
患者为44岁女性，诊断为IA期卵巢癌。在接受手术及紫杉醇和卡铂的两个周期化疗后，患者注意到下腹部隐痛，并在手术切口下方的皮下组织中发现一个肿块。诊断性活检显示为腹壁转移瘤。在接受22次分割、总剂量39.6 Gy的外照射放疗后，残留肿瘤在超声引导下接受间质近距离放射治疗。近距离放射治疗剂量为18 Gy，分6次给予，每次3 Gy。
结果
近距离放射治疗3周后，肿瘤完全消失。间质近距离放射治疗是可行的。
结论
间质近距离放射治疗可能是不可手术的浅表转移瘤，尤其是对低放射敏感性癌症的一种建议治疗策略。
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