乳腺癌胸壁难治性复发的组织间近距离治疗技术
Interstitial brachytherapy technique for chest wall refractory recurrence of breast cancer.
作者信息
Wu Ning, Chen Qianqian, Zhao Zhipeng, Zhao Hongfu, Cheng Guanghui
机构信息
These two authors contributed equally to this work.
Department of Radiation Oncology, China-Japan Union Hospital of Jilin University, Changchun, China.
出版信息
J Contemp Brachytherapy. 2015 Aug;7(4):290-4. doi: 10.5114/jcb.2015.53868. Epub 2015 Sep 14.
PURPOSE
To report the treatment effect of interstitial brachytherapy for chest wall locoregional recurrence of breast cancer.
MATERIAL AND METHODS
This 44-year-old female presented with chest wall recurrence seven years after modified radical mastectomy for stage II breast cancer. Despite external beam radiation and chemotherapy, the lesion expanded as 5.3 × 5.1 × 3.0 cm(3), and 8.0 × 5.1 × 4.0 cm(3). The locoregional recurrent tumor was treated with interstitial brachytherapy under ultrasound guidance. The brachytherapy dose was 30 Gy in 6 fractions of 5 Gy each.
RESULTS
Removal of the recurrent tumor was securely achieved by interstitial brachytherapy guided with ultrasound scanning. The refractory tumor in patient healed uneventfully after interstitial brachytherapy without recurrence during the 7 months of follow-up.
CONCLUSIONS
The ultrasound-guided interstitial brachytherapy may be effective for refractory recurrence of breast cancer.
目的
报告间质近距离放射治疗乳腺癌胸壁局部区域复发的治疗效果。
材料与方法
该44岁女性在II期乳腺癌改良根治术后7年出现胸壁复发。尽管接受了外照射放疗和化疗，但病灶仍扩大至5.3×5.1×3.0 cm³和8.0×5.1×4.0 cm³。在超声引导下对局部区域复发性肿瘤进行间质近距离放射治疗。近距离放射治疗剂量为30 Gy，分6次，每次5 Gy。
结果
通过超声扫描引导的间质近距离放射治疗成功切除复发性肿瘤。患者的难治性肿瘤在间质近距离放射治疗后顺利愈合，在7个月的随访期间无复发。
结论
超声引导下的间质近距离放射治疗可能对难治性乳腺癌复发有效。
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