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Duloxetine for the treatment of post-prostatectomy stress urinary incontinence.度洛西汀用于治疗前列腺切除术后压力性尿失禁。
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2
Postoperative phosphodiesterase type 5 inhibitor administration increases the rate of urinary continence recovery after bilateral nerve-sparing radical prostatectomy.术后磷酸二酯酶 5 抑制剂的应用可增加双侧保留神经的根治性前列腺切除术后尿控恢复率。
Int J Urol. 2013 Apr;20(4):413-9. doi: 10.1111/j.1442-2042.2012.03149.x. Epub 2012 Sep 12.
3
Post-radical-prostatectomy urinary incontinence: the management of concomitant bladder neck contracture.前列腺癌根治术后尿失禁:合并膀胱颈挛缩的处理
Adv Urol. 2012;2012:295798. doi: 10.1155/2012/295798. Epub 2012 Apr 26.
4
Artificial urinary sphincter: long-term results and patient satisfaction.人工尿道括约肌:长期效果及患者满意度
Adv Urol. 2012;2012:835290. doi: 10.1155/2012/835290. Epub 2012 Mar 26.
5
Surgery for stress urinary incontinence due to presumed sphincter deficiency after prostate surgery.前列腺手术后因推测括约肌功能不全导致的压力性尿失禁的手术治疗。
Cochrane Database Syst Rev. 2011 Apr 13(4):CD008306. doi: 10.1002/14651858.CD008306.pub2.
6
The excess burden of side-effects from treatment in men allocated to screening for prostate cancer. The Göteborg randomised population-based prostate cancer screening trial.治疗前列腺癌筛查男性患者的副作用所带来的过度负担。哥德堡随机人群前列腺癌筛查试验。
Eur J Cancer. 2011 Mar;47(4):545-53. doi: 10.1016/j.ejca.2010.10.016. Epub 2010 Nov 17.
7
Male urinary incontinence: prevalence, risk factors, and preventive interventions.男性尿失禁:患病率、危险因素及预防干预措施
Rev Urol. 2009 Summer;11(3):145-65.
8
Vardenafil can improve continence recovery after bilateral nerve sparing prostatectomy: results of a randomized, double blind, placebo-controlled pilot study.伐地那非可改善双侧保留神经前列腺切除术患者的控尿功能恢复:一项随机、双盲、安慰剂对照的初步研究结果。
J Sex Med. 2010 Jan;7(1 Pt 1):234-43. doi: 10.1111/j.1743-6109.2009.01471.x. Epub 2009 Sep 1.
9
Urinary incontinence following transurethral, transvesical and radical prostatectomy. Retrospective study of 489 patients.经尿道、经膀胱及根治性前列腺切除术后的尿失禁。对489例患者的回顾性研究。
Acta Urol Belg. 1997 Dec;65(4):1-7.

前列腺切除术后尿失禁区域服务报告:最佳实践模式?

A report of a regional service for post-prostatectomy urinary incontinence: a model for best practice?

作者信息

Almallah Y Zaki, Grimsley Samuel J S

机构信息

Department of Urology, Queen Elizabeth Hospital, University Hospital Birmingham NHS Foundation Trust, Edgbaston, Birmingham B15 2TH, UK.

Department of Urology, The Queen Elizabeth Hospital, University Hospital Birmingham NHS Foundation Trust, Edgbaston, Birmingham, UK.

出版信息

Ther Adv Urol. 2015 Apr;7(2):69-75. doi: 10.1177/1756287214561625.

DOI:10.1177/1756287214561625
PMID:25829950
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4372521/
Abstract

INTRODUCTION

Post-prostatectomy incontinence (PPI) is a potentially highly significant complication of a common urological procedure. Pathophysiology may be multifactorial but most commonly involves urinary sphincter weakness. The gold standard treatment for severe incontinence is artificial urinary sphincter but multiple alternatives exist. The growing incidence of PPI has led to the development of a specialized regional service dedicated to management.

PATIENTS AND METHODS

In 2004 a regional referral protocol for PPI was established with a dedicated clinic at a single centre for assessment and management including videourodynamics, pelvic floor rehabilitation, biofeedback and a consultant with a specialist interest in PPI surgery. Data regarding all in-house and tertiary referrals to this clinic between 2004 and 2011 were analysed with patients categorized by symptom severity.

RESULTS

A total of 267 patients were referred to the post-prostatectomy service (mean age 66.6, range 49-83 years) with numbers increasing year on year. Two-thirds of these were tertiary referrals: 27.7% of referrals were for mild symptoms, 35.2% moderate and 33.3% severe. One-third of referrals were made within 2 years of the primary procedure. Just over half of referred patients underwent invasive treatment including 24.3 artificial sphincter (24.3%) and male slings (22.8%). 7.5% patients were managed with medication, 14.6% were managed conservatively with containment therapy only. One-fifth remain under assessment or have deferred treatment.

CONCLUSION

PPI is of increasing personal and societal impact which should be identified early and supported. Investigation and management can be standardized and intervention at a high volume centre achieved by early specialist referral.

摘要

引言

前列腺切除术后尿失禁(PPI)是一种常见泌尿外科手术中潜在的极为严重的并发症。其病理生理学可能是多因素的,但最常见的是涉及尿道括约肌无力。严重尿失禁的金标准治疗方法是人工尿道括约肌,但也存在多种替代方法。PPI发病率的不断上升促使专门设立了一个致力于管理的区域服务机构。

患者与方法

2004年制定了PPI区域转诊方案,在单一中心设立了专门诊所进行评估和管理,包括影像尿动力学、盆底康复、生物反馈以及一位对PPI手术有专业兴趣的顾问。分析了2004年至2011年期间转诊至该诊所的所有内部和三级转诊患者的数据,并根据症状严重程度对患者进行分类。

结果

共有267例患者转诊至前列腺切除术后服务机构(平均年龄66.6岁,范围49 - 83岁),人数逐年增加。其中三分之二是三级转诊:27.7%的转诊患者症状较轻,35.2%为中度,33.3%为重度。三分之一的转诊是在初次手术后2年内进行的。略超过一半的转诊患者接受了侵入性治疗,包括24.3%植入人工括约肌和22.8%使用男性吊带。7.5%的患者接受药物治疗,14.6%仅采用尿垫治疗进行保守处理。五分之一的患者仍在接受评估或推迟了治疗。

结论

PPI对个人和社会的影响日益增加,应尽早识别并给予支持。通过早期专科转诊,在大容量中心可以实现调查和管理的标准化以及干预。