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沙特阿拉伯东部省下呼吸道感染患儿人博卡病毒血症的临床描述

Clinical description of human bocavirus viremia in children with LRTI, Eastern Province, Saudi Arabia.

作者信息

Bubshait Dalal K, Albuali Waleed Hamad, Yousef Abdullah A, Obeid Obeid Elteifi, Alkharsah Khaled R, Hassan Manal Ismaeel, Vatte Chittibabu, Alzahrani Alhusain J, Bukhari Huda

机构信息

Department of Pediatrics, University of Dammam, Dammam, Saudi Arabia.

Department of Microbiology, University of Dammam, Dammam, Saudi Arabia.

出版信息

Ann Thorac Med. 2015 Apr-Jun;10(2):146-9. doi: 10.4103/1817-1737.151437.

Abstract

Human bocavirus (HBoV) is a major etiology of lower respiratory tract infection (LRTI) in young children. We tested 149 patients admitted to King Fahd Hospital of the University with diagnosis of LRTI. Viremia caused by the different studied viruses was detected in 31.5% of the total cases by Real-time Polymerase chain reaction. We report five patients who were positive for HBoV in serum samples. Clinical presentation ranged from mild to severe disease as one of them required admission to intensive care unit. Wheezing was a striking feature in most of our patients, but fever was not a consistent finding.

摘要

人博卡病毒(HBoV)是幼儿下呼吸道感染(LRTI)的主要病因。我们对法赫德国王大学医院收治的149例诊断为LRTI的患者进行了检测。通过实时聚合酶链反应在31.5%的总病例中检测到了由不同研究病毒引起的病毒血症。我们报告了5例血清样本中HBoV呈阳性的患者。临床表现从轻度到重度不等,其中1例需要入住重症监护病房。喘鸣是我们大多数患者的一个显著特征,但发热并非一致的表现。

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