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A case of pediatric ALL with t(16;21)(p11.2;q22) and FUS-ERG rearrangement.

作者信息

Coccé Mariela C, Alonso Cristina N, Rossi Jorge, Felice Maria S, Gitter Myriam R, Gallego Marta S

机构信息

Servicio de Genética. Hospital de Pediatría "Prof. Dr. J. P. Garrahan", Buenos Aires, Argentina.

Servicio de Hemato-Oncología. Hospital de Pediatría "Prof. Dr. J. P. Garrahan", Buenos Aires, Argentina.

出版信息

Blood Res. 2015 Mar;50(1):55-8. doi: 10.5045/br.2015.50.1.55. Epub 2015 Mar 24.

DOI:10.5045/br.2015.50.1.55
PMID:25830133
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4377342/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e73b/4377342/e3767cd7a45e/br-50-55-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e73b/4377342/8fc12341f418/br-50-55-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e73b/4377342/e3767cd7a45e/br-50-55-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e73b/4377342/8fc12341f418/br-50-55-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e73b/4377342/e3767cd7a45e/br-50-55-g002.jpg

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本文引用的文献

1
Detection and clinical significance of gene rearrangements in Chinese patients with adult acute lymphoblastic leukemia.检测中国成人急性淋巴细胞白血病患者中的基因重排及其临床意义。
Leuk Lymphoma. 2013 Jul;54(7):1521-6. doi: 10.3109/10428194.2012.754888. Epub 2013 Jan 7.
2
Two childhood cases of acute leukemia with t(16;21)(p11.2;q22): second case report of infantile acute lymphoblastic leukemia with unusual type of FUS-ERG chimeric transcript.两例伴有t(16;21)(p11.2;q22)的儿童急性白血病:婴儿急性淋巴细胞白血病伴不寻常类型FUS-ERG嵌合转录本的第二例报告
Cancer Genet Cytogenet. 2010 Jul 15;200(2):180-3. doi: 10.1016/j.cancergencyto.2010.04.009.
3
Cytogenetic and Molecular Findings in Children with Acute Lymphoblastic Leukemia: Experience of a Single Institution in Argentina.
急性淋巴细胞白血病患儿的细胞遗传学和分子学研究结果:阿根廷一家机构的经验
Mol Syndromol. 2015 Oct;6(4):193-203. doi: 10.1159/000441046. Epub 2015 Oct 7.
TLS/FUS-ERG fusion gene in acute lymphoblastic leukemia with t(16;21)(p11;q22) and monitoring of minimal residual disease.
伴有t(16;21)(p11;q22)的急性淋巴细胞白血病中的TLS/FUS-ERG融合基因及微小残留病监测
Leuk Lymphoma. 2005 Dec;46(12):1833-5. doi: 10.1080/10428190500162203.
4
Breakpoint differentiation in chromosomal aberrations of hematological malignancies: Identification of 33 previously unrecorded breakpoints.血液系统恶性肿瘤染色体畸变中的断点区分:鉴定33个先前未记录的断点。
Int J Oncol. 2004 Jan;24(1):127-36.
5
Standardized RT-PCR analysis of fusion gene transcripts from chromosome aberrations in acute leukemia for detection of minimal residual disease. Report of the BIOMED-1 Concerted Action: investigation of minimal residual disease in acute leukemia.用于检测急性白血病微小残留病的染色体畸变融合基因转录本的标准化逆转录聚合酶链反应分析。BIOMED-1协同行动报告:急性白血病微小残留病的研究。
Leukemia. 1999 Dec;13(12):1901-28. doi: 10.1038/sj.leu.2401592.
6
Consistent detection of TLS/FUS-ERG chimeric transcripts in acute myeloid leukemia with t(16;21)(p11;q22) and identification of a novel transcript.在伴有t(16;21)(p11;q22)的急性髓系白血病中持续检测到TLS/FUS-ERG嵌合转录本并鉴定出一种新的转录本。
Blood. 1997 Aug 1;90(3):1192-9.
7
An RNA-binding protein gene, TLS/FUS, is fused to ERG in human myeloid leukemia with t(16;21) chromosomal translocation.在伴有t(16;21)染色体易位的人类髓系白血病中,一种RNA结合蛋白基因TLS/FUS与ERG融合。
Cancer Res. 1994 Jun 1;54(11):2865-8.