• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

Chronic eosinophilic leukemia with a FIP1L1-PDGFRA rearrangement: Two case reports and a review of Korean cases.

作者信息

Shin Sang-Yong, Jung Chul-Won, Choi Dong-Chull, Lee Byung-Jae, Kim Hee-Jin, Kim Sun-Hee

机构信息

Department of Laboratory Medicine & Genetics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

Department of Internal Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

出版信息

Blood Res. 2015 Mar;50(1):58-61. doi: 10.5045/br.2015.50.1.58. Epub 2015 Mar 24.

DOI:10.5045/br.2015.50.1.58
PMID:25830134
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4377343/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e96f/4377343/c72ca22cfd0a/br-50-58-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e96f/4377343/b3b49b2ca0c0/br-50-58-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e96f/4377343/c72ca22cfd0a/br-50-58-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e96f/4377343/b3b49b2ca0c0/br-50-58-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e96f/4377343/c72ca22cfd0a/br-50-58-g002.jpg

相似文献

1
Chronic eosinophilic leukemia with a FIP1L1-PDGFRA rearrangement: Two case reports and a review of Korean cases.伴有FIP1L1-PDGFRA重排的慢性嗜酸性粒细胞白血病:两例病例报告及韩国病例综述
Blood Res. 2015 Mar;50(1):58-61. doi: 10.5045/br.2015.50.1.58. Epub 2015 Mar 24.
2
Synchronous FIP1L1-PDGFRA-positive chronic eosinophilic leukemia and T-cell lymphoblastic lymphoma: a bilineal clonal malignancy.同步FIP1L1-PDGFRA阳性慢性嗜酸性粒细胞白血病和T细胞淋巴母细胞淋巴瘤:一种双系克隆性恶性肿瘤。
Eur J Haematol. 2008 Jan;80(1):81-6. doi: 10.1111/j.1600-0609.2007.00973.x. Epub 2007 Nov 19.
3
The severity of FIP1L1-PDGFRA-positive chronic eosinophilic leukaemia is associated with polymorphic variation at the IL5RA locus.FIP1L1-PDGFRA阳性慢性嗜酸性粒细胞白血病的严重程度与IL5RA基因座的多态性变异相关。
Leukemia. 2007 Dec;21(12):2428-32. doi: 10.1038/sj.leu.2404977. Epub 2007 Oct 4.
4
Clinical and molecular features of FIP1L1-PDFGRA (+) chronic eosinophilic leukemias.FIP1L1-PDFGRA(+)慢性嗜酸性粒细胞白血病的临床和分子特征
Leukemia. 2004 Apr;18(4):734-42. doi: 10.1038/sj.leu.2403313.
5
A novel FIP1L1-PDGFRA mutant destabilizing the inactive conformation of the kinase domain in chronic eosinophilic leukemia/hypereosinophilic syndrome.一种新型FIP1L1-PDGFRA突变体,可破坏慢性嗜酸性粒细胞白血病/高嗜酸性粒细胞综合征中激酶结构域的非活性构象。
Allergy. 2009 Jun;64(6):913-8. doi: 10.1111/j.1398-9995.2009.01943.x. Epub 2009 Feb 7.
6
A case of FIP1L1-PDGFRA-positive chronic eosinophilic leukemia with a rare FIP1L1 breakpoint.一例具有罕见FIP1L1断点的FIP1L1-PDGFRA阳性慢性嗜酸性粒细胞白血病
J Mol Diagn. 2007 Jul;9(3):414-9. doi: 10.2353/jmoldx.2007.060196.
7
[Characteristics of cytogenetics and molecular biology in patients with eosinophilia].嗜酸性粒细胞增多症患者的细胞遗传学和分子生物学特征
Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2012 Oct;20(5):1216-20.
8
Imatinib therapy in acute myeloid leukemia with DEK-NUP214 and FIP1L1-PDGFRA rearrangement: A case report.伊马替尼治疗伴有DEK-NUP214和FIP1L1-PDGFRA重排的急性髓系白血病:一例报告
Oncol Lett. 2020 May;19(5):3587-3592. doi: 10.3892/ol.2020.11455. Epub 2020 Mar 10.
9
Detection of the FIP1L1-PDGFRA fusion in idiopathic hypereosinophilic syndrome and chronic eosinophilic leukemia.特发性嗜酸性粒细胞增多综合征和慢性嗜酸性粒细胞白血病中FIP1L1-PDGFRA融合基因的检测
Methods Mol Med. 2006;125:177-87. doi: 10.1385/1-59745-017-0:177.
10
FIP1L1-PDGFRA in chronic eosinophilic leukemia and BCR-ABL1 in chronic myeloid leukemia affect different leukemic cells.慢性嗜酸性粒细胞白血病中的FIP1L1-PDGFRA和慢性髓性白血病中的BCR-ABL1影响不同的白血病细胞。
Leukemia. 2007 Mar;21(3):397-402. doi: 10.1038/sj.leu.2404510. Epub 2007 Jan 11.

引用本文的文献

1
Loeffler endocarditis revealing chronic eosinophilic leukaemia with FIP1L1-PDGFRA rearrangement: a case report.以伴有FIP1L1-PDGFRA重排的慢性嗜酸性粒细胞白血病为表现的勒夫勒心内膜炎:一例报告
Eur Heart J Case Rep. 2025 May 2;9(5):ytaf218. doi: 10.1093/ehjcr/ytaf218. eCollection 2025 May.
2
Loeffler endocarditis in chronic eosinophilic leukemia with FIP1L1/PDGFRA rearrangement: full recovery with low dose imatinib.伴有FIP1L1/PDGFRA重排的慢性嗜酸性粒细胞白血病中的勒夫勒心内膜炎:低剂量伊马替尼治疗后完全康复
Korean J Intern Med. 2018 May;33(3):642-644. doi: 10.3904/kjim.2016.100. Epub 2017 Jun 28.
3
Chronic eosinophilic leukemia with rearrangement.

本文引用的文献

1
A case of idiopathic hypereosinophilic syndrome presenting with acute respiratory distress syndrome.特发性嗜酸性粒细胞增多综合征致急性呼吸窘迫综合征 1 例
Allergy Asthma Immunol Res. 2014 Jan;6(1):98-101. doi: 10.4168/aair.2014.6.1.98. Epub 2013 Sep 27.
2
Acute myeloid leukemia associated with FGFR1 abnormalities.伴有 FGFR1 异常的急性髓系白血病。
Int J Hematol. 2013 Jun;97(6):808-12. doi: 10.1007/s12185-013-1337-5. Epub 2013 Apr 23.
3
Hypereosinophilic syndrome: a multicenter, retrospective analysis of clinical characteristics and response to therapy.
伴有重排的慢性嗜酸性粒细胞白血病
Blood Res. 2016 Sep;51(3):204-206. doi: 10.5045/br.2016.51.3.204. Epub 2016 Sep 23.
嗜酸性粒细胞增多综合征:一项多中心回顾性分析临床特征和治疗反应。
J Allergy Clin Immunol. 2009 Dec;124(6):1319-25.e3. doi: 10.1016/j.jaci.2009.09.022.
4
[Incidence and causes of hypereosinophilia (corrected) in the patients of a university hospital].[某大学医院患者中嗜酸性粒细胞增多症(校正后)的发病率及病因]
Korean J Lab Med. 2009 Jun;29(3):185-93. doi: 10.3343/kjlm.2009.29.3.185.
5
Five years since the discovery of FIP1L1-PDGFRA: what we have learned about the fusion and other molecularly defined eosinophilias.发现FIP1L1-PDGFRA五年以来:我们对该融合基因及其他分子定义的嗜酸性粒细胞增多症的了解
Leukemia. 2008 Nov;22(11):1999-2010. doi: 10.1038/leu.2008.287. Epub 2008 Oct 9.
6
8p11 myeloproliferative syndrome preceded by t(8;9)(p11;q33), CEP110/FGFR1 fusion transcript: morphologic, molecular, and cytogenetic characterization of myeloid neoplasms associated with eosinophilia and FGFR1 abnormality.伴有t(8;9)(p11;q33)、CEP110/FGFR1融合转录本的8p11骨髓增殖综合征:与嗜酸性粒细胞增多和FGFR1异常相关的髓系肿瘤的形态学、分子学和细胞遗传学特征
Cancer Genet Cytogenet. 2008 Mar;181(2):93-9. doi: 10.1016/j.cancergencyto.2007.11.011.
7
A case of chronic myelomonocytic leukemia with severe eosinophilia having t(5;12)(q31;p13) with t(1;7)(q10;p10).一例慢性粒单核细胞白血病伴严重嗜酸性粒细胞增多症,存在t(5;12)(q31;p13)和t(1;7)(q10;p10)。
Acta Haematol. 2005;114(2):104-7. doi: 10.1159/000086584.
8
CHIC2 deletion, a surrogate for FIP1L1-PDGFRA fusion, occurs in systemic mastocytosis associated with eosinophilia and predicts response to imatinib mesylate therapy.CHIC2缺失作为FIP1L1-PDGFRA融合的替代指标,见于伴有嗜酸性粒细胞增多的系统性肥大细胞增多症,并可预测对甲磺酸伊马替尼治疗的反应。
Blood. 2003 Nov 1;102(9):3093-6. doi: 10.1182/blood-2003-05-1627. Epub 2003 Jul 3.