Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Allergy Asthma Immunol Res. 2014 Jan;6(1):98-101. doi: 10.4168/aair.2014.6.1.98. Epub 2013 Sep 27.
Although idiopathic hypereosinophilic syndrome(IHES) commonly involves the lung, it is rarely associated with acute respiratory distress syndrome (ARDS). Here we describe a case of IHES presented in conjunction with ARDS. A 37-year-old male visited the emergency department at Samsung Medical Center, Seoul, Korea, with a chief complaint of dyspnea. Blood tests showed profound peripheral eosinophilia and thrombocytopenia. Patchy areas of consolidation with ground-glass opacity were noticed in both lower lung zones on chest radiography. Rapid progression of dyspnea and hypoxia despite supplement of oxygen necessitated the use of mechanical ventilation. Eosinophilic airway inflammation was subsequently confirmed by bronchoalveolar lavage, leading to a diagnosis of IHES. High-dose corticosteroids were administered, resulting in a dramatic clinical response.
虽然特发性嗜酸性粒细胞增多综合征（IHES）常累及肺部，但很少与急性呼吸窘迫综合征（ARDS）相关。本文描述了一例同时伴有 ARDS 的 IHES 病例。一名 37 岁男性因呼吸困难到韩国首尔三星医疗中心急诊就诊。血液检查显示外周血嗜酸性粒细胞和血小板显著增多。胸部 X 线显示双肺下区斑片状实变伴磨玻璃影。尽管吸氧补充，但呼吸困难和缺氧仍迅速进展，需要使用机械通气。支气管肺泡灌洗随后证实为嗜酸性气道炎症，从而诊断为 IHES。给予大剂量皮质类固醇治疗，临床反应显著。
