Orlov Iu P, Lukach V N, Govorova N V
Anesteziol Reanimatol. 2014 Nov-Dec;59(6):67-72.
The review deals with a modern view of iron exchange in general and during pregnancy, in particular Different views on the mechanisms of the development of anemia in pregnancy are reflected. The protective role of anemia is noted, and also the opinion of the review authors to the negative role of prophylactic supplementation of iron is reflected. Are numerous and compelling scientific evidence pointing to the large number of negative prevention of iron. That questioned the usefulness of routine appointments for pregnant women with iron. According to a large number of studies assigning pregnant iron on the one hand, contributes to excessive activation of free radical oxidation, the accumulation of lipid peroxidation products and demonstrations of eclampsia, and from the other potentiates the bacterial aggression and development of purulent-septic diseases that generally leads to the development of complications in pregnancy.
这篇综述探讨了铁交换的现代观点,总体而言以及在孕期的情况,特别反映了关于孕期贫血发生机制的不同观点。文中提到了贫血的保护作用,也反映了综述作者对预防性补充铁剂负面作用的看法。有大量令人信服的科学证据表明大量预防性补充铁剂存在诸多负面影响。这质疑了对孕妇常规补充铁剂的有效性。根据大量研究,一方面给孕妇补铁会导致自由基氧化过度激活、脂质过氧化产物积累以及子痫的发生,另一方面会增强细菌侵袭力并引发化脓性败血症,总体上会导致孕期并发症的发生。