肺实性肿瘤合并肺曲霉菌病：病例报告及文献复习
Pulmonary solid tumor with coexisting pulmonary aspergillosis: case reports and literature review.
作者信息
Wu Ting, Li Pei, Wang Min, Wang Qin, Shi Yi, Su Xin
机构信息
Department of Respiratory and Critical Care Medicine, Jinling Hospital, Nanjing University School of Medicine, Nanjing, China.
Department of Critical Care Medicine, No. 81 Hospital of PLA, Nanjing, China.
出版信息
Clin Respir J. 2017 Jan;11(1):3-12. doi: 10.1111/crj.12294. Epub 2015 Apr 28.
BACKGROUND AND AIMS
The association of noncavitary untreated lung cancer with coexisting pulmonary Aspergillosis in immunocompetent patients is an extremely rare occurrence. The present paper aims to summarize the clinical data, and gives an overview of the current knowledge on the etiology, diagnosis and treatment of this condition.
METHODS
We report four cases and review seven cases in the literature.
RESULTS
The four cases describe pulmonary solid tumor with coexisting pulmonary Aspergillosis condition. All cases underwent complicated procession for the terminal diagnosis.
CONCLUSION
Clinicians should be alert to underlying malignant disease if airway Aspergillus infection is suspicious in a patient without strong risk factors for invasive fungal disease. On the other hand, when lung cancer is coexisting with airway necrotizing Aspergillosis, clinicians should properly manage these two diseases simultaneously.
背景与目的
在免疫功能正常的患者中，非空洞性未经治疗的肺癌与并存的肺曲霉菌病相关联的情况极为罕见。本文旨在总结临床数据，并概述关于这种情况的病因、诊断和治疗的现有知识。
方法
我们报告了4例病例，并回顾了文献中的7例病例。
结果
这4例病例描述了伴有并存肺曲霉菌病情况的肺部实性肿瘤。所有病例均经历了复杂的诊断过程才最终确诊。
结论
如果在没有侵袭性真菌病强烈危险因素的患者中怀疑气道曲霉菌感染，临床医生应警惕潜在的恶性疾病。另一方面，当肺癌与气道坏死性曲霉菌病并存时，临床医生应同时妥善处理这两种疾病。
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