Zhu Chen, Liu Xiuli, Gu Ying, Shen Yuyao, Jiang Tingshu
Department of Respiratory and Critical Care Medicine, Yantai Yuhuangding Hospital, Yantai, China.
Front Med (Lausanne). 2025 Aug 13;12:1660190. doi: 10.3389/fmed.2025.1660190. eCollection 2025.
This study aimed to explore the clinical characteristics, diagnosis, and management of Invasive Pulmonary (IPA) complicating empyema in a patient with lung cancer.
We analyzed the clinical manifestations, bronchoscopic findings, and therapeutic approaches, including anti-infective and anti-tumor treatments, in a patient diagnosed with IPA-associated empyema and lung cancer. Histopathological examination of bronchoscopic biopsy specimens confirmed pulmonary adenocarcinoma, while bronchoalveolar lavage fluid cultures identified . Following the development of secondary empyema, comprehensive anti-infective and anti-tumor therapies were administered, leading to disease control. IPA-associated empyema complicating lung cancer represents a rare clinical scenario.
In patients presenting with IPA, the potential coexistence of lung cancer should be considered. An integrated approach combining antifungal therapy and active anti-tumor treatment is essential for managing such cases.
本研究旨在探讨肺癌患者并发侵袭性肺曲霉病（IPA）合并脓胸的临床特征、诊断及治疗。
我们分析了一名诊断为IPA相关脓胸和肺癌患者的临床表现、支气管镜检查结果及治疗方法，包括抗感染和抗肿瘤治疗。支气管镜活检标本的组织病理学检查确诊为肺腺癌，而支气管肺泡灌洗液培养鉴定出……。继发脓胸后，给予综合抗感染和抗肿瘤治疗，病情得到控制。IPA相关脓胸合并肺癌是一种罕见的临床情况。
对于出现IPA的患者，应考虑肺癌共存的可能性。抗真菌治疗与积极的抗肿瘤治疗相结合的综合方法对于处理此类病例至关重要。
