Seidman D S, Ever-Hadani P, Stevenson D K, Gale R
Department of Neonatology, Bikur Cholim Hospital, Jerusalem, Israel.
Eur J Obstet Gynecol Reprod Biol. 1989 Nov;33(2):109-14. doi: 10.1016/0028-2243(89)90203-7.
The incidence of pre-eclampsia was studied in 9771 women that were pregnant for the first or second time. The protection offered by a previous pregnancy which ended in abortion was compared to that provided by a first pregnancy that proceeded to term. The rate of pre-eclampsia was 2.9% for primigravid women and was significantly lower (1.5%, p less than 0.001) for women giving birth for the second time. Adjusting by multiple regression for confounding factors (e.g., maternal age, social class, ethnic origin and smoking), the incidence of pre-eclampsia was also significantly lower (p = 0.038) following an induced abortion, but not following a spontaneous abortion.
对9771名首次或第二次怀孕的女性进行了先兆子痫发病率的研究。将先前以流产告终的怀孕所提供的保护与首次足月分娩的怀孕所提供的保护进行了比较。初产妇先兆子痫的发生率为2.9%，经产妇的发生率显著较低（1.5%，p<0.001）。通过多元回归对混杂因素（如产妇年龄、社会阶层、种族和吸烟）进行调整后，人工流产后先兆子痫的发生率也显著较低（p=0.038），但自然流产后并非如此。
