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Liver transplantation for giant hepatic angiomyolipoma.巨大肝脏血管平滑肌脂肪瘤的肝移植术
Liver Transpl. 2011 Aug;17(8):985-6. doi: 10.1002/lt.22310.
2
Liver transplantation for multiple angiomyolipomas complicating tuberous sclerosis complex.
Gastroenterol Clin Biol. 2010 Sep;34(8-9):494-8. doi: 10.1016/j.gcb.2010.06.005. Epub 2010 Jul 31.
3
Renal epithelioid angiomyolipoma with atypia: a series of 40 cases with emphasis on clinicopathologic prognostic indicators of malignancy.具有非典型性的肾上皮样血管平滑肌脂肪瘤:40 例系列病例,重点在于恶性肿瘤的临床病理预后指标。
Am J Surg Pathol. 2010 May;34(5):715-22. doi: 10.1097/PAS.0b013e3181d90370.
4
Malignant angiomyolipoma in the liver: a case report with pathological and molecular analysis.肝脏恶性血管平滑肌脂肪瘤:一例伴有病理及分子分析的病例报告
Pathol Res Pract. 2008;204(12):911-8. doi: 10.1016/j.prp.2008.06.007. Epub 2008 Aug 23.
5
Management of hepatic angiomyolipoma.肝血管平滑肌脂肪瘤的管理
J Gastrointest Surg. 2007 Apr;11(4):452-7. doi: 10.1007/s11605-006-0037-3.
6
Malignant neoplasm of perivascular epithelioid cells of the liver.肝脏血管周上皮样细胞恶性肿瘤
Arch Pathol Lab Med. 2006 Aug;130(8):1219-22. doi: 10.5858/2006-130-1219-MNOPEC.
7
Growth of hepatic angiomyolipoma indicating malignant potential.肝脏血管平滑肌脂肪瘤的生长提示恶性潜能。
J Gastroenterol Hepatol. 2004 Nov;19(11):1328-30. doi: 10.1111/j.1440-1746.2004.03583.x.
8
Malignant angiomyolipoma of the liver: a hitherto unreported variant.肝脏恶性血管平滑肌脂肪瘤:一种迄今未报道的变异型。
Histopathology. 2000 May;36(5):443-50. doi: 10.1046/j.1365-2559.2000.00891.x.
9
Orthotopic liver transplantation for benign hepatic neoplasms.良性肝脏肿瘤的原位肝移植
Arch Surg. 1995 Feb;130(2):153-6. doi: 10.1001/archsurg.1995.01430020043005.

肝切除术后复发性恶性肝血管平滑肌脂肪瘤的肝移植:一例报告

Liver transplantation for recurrent posthepatectomy malignant hepatic angiomyolipoma: a case report.

作者信息

Wang Wen-Tao, Li Zi-Qiang, Zhang Gui-Hui, Guo Yuan, Teng Mu-Jian

机构信息

Wen-Tao Wang, Zi-Qiang Li, Gui-Hui Zhang, Yuan Guo, Mu-Jian Teng, Department of Hepatobiliary Surgery, Shandong Provincial Qianfoshan Hospital, Shandong University, Jinan 250014, Shandong Province, China.

出版信息

World J Gastroenterol. 2015 Mar 28;21(12):3755-8. doi: 10.3748/wjg.v21.i12.3755.

DOI:10.3748/wjg.v21.i12.3755
PMID:25834347
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4375604/
Abstract

Hepatic angiomyolipomas (AMLs) are typically benign tumors containing varying amounts of smooth muscle cells, adipose tissue, and vessels, and are commonly found in the kidney and occasionally in the liver. The preoperative diagnosis of hepatic AML is primarily made from imaging and fine-needle aspiration biopsy results, though limited experience for such diagnoses can result in misdiagnosis. Some uncommon features of hepatic AML have been reported in the literature without an objective or qualitative consensus. As the majority of cases are benign, conservative treatment of AMLs is recommended. However, in rare cases, liver transplantation has been implemented. Only five cases of malignant hepatic AML have been reported. We report a rare case of recurrent posthepatectomy malignant hepatic AML that was misdiagnosed as liver cancer in a 37-year-old woman, which was treated by liver transplantation. The imaging and pathologic findings are presented in order to provide a more concise description to aid in future diagnoses.

摘要

肝脏血管平滑肌脂肪瘤(AMLs)是一种典型的良性肿瘤,由不同数量的平滑肌细胞、脂肪组织和血管构成,常见于肾脏,偶尔也见于肝脏。肝脏AML的术前诊断主要依据影像学检查和细针穿刺活检结果,但由于此类诊断经验有限,可能会导致误诊。文献中报道了一些肝脏AML的罕见特征,但尚未达成客观或定性的共识。由于大多数病例为良性,建议对AMLs进行保守治疗。然而,在罕见情况下,也会实施肝移植。目前仅报道了5例恶性肝脏AML。我们报告了一例罕见的复发性肝切除术后恶性肝脏AML病例,该病例发生在一名37岁女性身上,术前被误诊为肝癌,最终接受了肝移植治疗。本文展示了其影像学和病理学检查结果,以便提供更简洁的描述,辅助未来的诊断。