Moghadasi Mehrzad, Mohammadi Domieh Amin
Department of Exercise Physiology, Shiraz branch, Islamic Azad University, Shiraz, Iran.
Department of Exercise Physiology, Gachsaran branch, Islamic Azad University, Gachsaran, Iran.
Asian J Sports Med. 2014 Jun;5(2):108-14.
Lipocalin-2 (Lcn2) has been recognized as an adipocyte-derived acute phase protein that is positively correlated with obesity, insulin resistance, type 2 diabetes, and cardiovascular disease. The effects of resistance and endurance training (RT vs. ET) on plasma lipocalin-2 are still unclear. Therefore, the purpose of this study was to examine the effects of RT vs. ET on plasma lipocalin-2 in young men.
Twenty nine healthy and sedentary young men (age, 21-29 years) participated in this study. The subjects were randomly assigned to RT group (n=9), ET group (n=10) or control group (n=10). The experimental groups performed either RT or ET, 3 days a week for 8 weeks. The endurance training program included continuous running at an intensity corresponding to 65-80% of maximal heart rate, while resistance training consisted of 2-4 sets of circuit weight training for 8 stations and at an intensity corresponding to 65-80% of 1-RM in each station.
No significant changes in the body mass, BMI, body fat percentage and WHR were found after the RT and ET. The results showed that Lcn2 decreased after RT and ET compared with the control group (P<0.05). High sensitivity C-reactive protein (hs-CRP) and insulin resistance determined by HOMA-IR, did not change in the RT and ET compared with the control group.
Lcn2 decreases after 8 weeks RT and ET, but this improvement was not accompanied by decreased hs-CRP and insulin resistance in healthy and sedentary young men.
脂质运载蛋白-2（Lcn2）已被公认为是一种源自脂肪细胞的急性期蛋白，与肥胖、胰岛素抵抗、2型糖尿病和心血管疾病呈正相关。抗阻训练与耐力训练（RT与ET）对血浆脂质运载蛋白-2的影响仍不清楚。因此，本研究的目的是探讨RT与ET对年轻男性血浆脂质运载蛋白-2的影响。
29名健康且久坐不动的年轻男性（年龄21 - 29岁）参与了本研究。受试者被随机分为抗阻训练组（n = 9）、耐力训练组（n = 10）或对照组（n = 10）。实验组每周进行3天的RT或ET训练，持续8周。耐力训练计划包括以相当于最大心率65 - 80%的强度持续跑步，而抗阻训练包括对8个训练站进行2 - 4组循环重量训练，每个训练站的强度相当于1次重复最大值（1-RM）的65 - 80%。
RT和ET后，体重、BMI、体脂百分比和腰臀比均无显著变化。结果显示，与对照组相比，RT和ET后Lcn2降低（P<0.05）。与对照组相比，RT和ET中由HOMA-IR测定的高敏C反应蛋白（hs-CRP）和胰岛素抵抗没有变化。
在健康且久坐不动的年轻男性中，8周的RT和ET后Lcn2降低，但这种改善并未伴随着hs-CRP和胰岛素抵抗的降低。
