Bergmann W, Heller W, Hoffmeister H E
Chirurgische Universitätsklinik, Tübingen, W. Germany.
Free Radic Res Commun. 1989;7(3-6):355-66. doi: 10.3109/10715768909087962.
In our studies with simulated extracorporeal blood circulation we observed damaging effects on blood cells, especially under oxygenating conditions. In order to characterize these effects we also analysed electrolyte and trace-element concentrations in plasma during and after simulated extracorporeal blood circulation. Highest resorption effects for magnesium and highest desorption effects for calcium, copper and iron are found with oxygen gas flow in the system. Membrane permeability for electrolytes seems to be induced as well. Cellular damage due only to mechanical stress within the perfusion system can be neglected.
在我们对模拟体外血液循环的研究中，我们观察到对血细胞有破坏作用，尤其是在氧合条件下。为了表征这些影响，我们还分析了模拟体外血液循环期间及之后血浆中的电解质和微量元素浓度。在系统中有氧气流时，发现镁的吸收作用最强，而钙、铜和铁的解吸作用最强。电解质的膜通透性似乎也被诱导。仅由灌注系统内机械应力导致的细胞损伤可忽略不计。
