Lally Lindsay, Spiera Robert F
Division of Rheumatology, Hospital for Special Surgery, 535 East 70th Street, New York, NY 10021, USA.
Division of Rheumatology, Hospital for Special Surgery, 535 East 70th Street, New York, NY 10021, USA.
Rheum Dis Clin North Am. 2015 May;41(2):315-31. doi: 10.1016/j.rdc.2015.01.004. Epub 2015 Feb 27.
Pulmonary vasculitis encompasses inflammation in the pulmonary vasculature with involved vessels varying in caliber from large elastic arteries to capillaries. Small pulmonary capillaries are the vessels most commonly involved in vasculitis affecting the lung. The antineutrophil cytoplasmic antibody-associated vasculitides, which include granulomatosis with polyangiitis (formerly Wegener granulomatosis), microscopic polyangiitis, and eosinophilic granulomatosis with polyangiitis (formerly Churg-Strauss syndrome), are the small vessel vasculitides in which pulmonary vasculitis is most frequently observed and are the major focus of this review. Vasculitic involvement of the large pulmonary vessels as may occur in Behçet syndrome and Takayasu arteritis is also discussed.
肺血管炎包括肺血管系统的炎症，受累血管的管径大小不一，从大的弹性动脉到毛细血管。小的肺毛细血管是肺部血管炎最常累及的血管。抗中性粒细胞胞浆抗体相关血管炎，包括肉芽肿性多血管炎（以前称为韦格纳肉芽肿病）、显微镜下多血管炎和嗜酸性肉芽肿性多血管炎（以前称为变应性肉芽肿性血管炎），是最常观察到肺血管炎的小血管血管炎，也是本综述的主要重点。本文还讨论了白塞病和大动脉炎中可能出现的大肺血管的血管炎累及情况。
