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Illicit buprenorphine use, interest in and access to buprenorphine treatment among syringe exchange participants.注射器交换项目参与者中非法使用丁丙诺啡的情况、对丁丙诺啡治疗的兴趣及获取途径。
J Subst Abuse Treat. 2015 Jan;48(1):112-6. doi: 10.1016/j.jsat.2014.07.015. Epub 2014 Aug 7.
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Pharmaceutical overdose deaths, United States, 2010.2010年美国药物过量致死情况
JAMA. 2013 Feb 20;309(7):657-9. doi: 10.1001/jama.2013.272.
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Opioid maintenance treatment as a harm reduction tool for opioid-dependent individuals in New York City: the need to expand access to buprenorphine/naloxone in marginalized populations.阿片类药物维持治疗作为纽约市阿片类药物依赖者的减少伤害工具:有必要扩大在边缘化人群中使用丁丙诺啡/纳洛酮的机会。
J Addict Dis. 2012;31(3):278-87. doi: 10.1080/10550887.2012.694603.
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Illicit use of buprenorphine/naloxone among injecting and noninjecting opioid users.阿片类药物使用者中丁丙诺啡/纳洛酮的非法使用。
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Syringe exchange programs --- United States, 2008.注射器交换项目——美国,2008 年。
MMWR Morb Mortal Wkly Rep. 2010 Nov 19;59(45):1488-91.
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Heroin-dependent inmates' experiences with buprenorphine or methadone maintenance.海洛因依赖囚犯使用丁丙诺啡或美沙酮维持治疗的体验。
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Buprenorphine maintenance versus placebo or methadone maintenance for opioid dependence.丁丙诺啡维持治疗与安慰剂或美沙酮维持治疗用于阿片类药物依赖的比较
Cochrane Database Syst Rev. 2004(3):CD002207. doi: 10.1002/14651858.CD002207.pub2.
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An invisible barrier to integrating HIV primary care with harm reduction services: philosophical clashes between the harm reduction and medical models.将艾滋病病毒初级护理与减少伤害服务相结合的无形障碍:减少伤害模式与医学模式之间的理念冲突。
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减少伤害机构作为丁丙诺啡治疗的潜在场所。

Harm Reduction Agencies as a Potential Site for Buprenorphine Treatment.

作者信息

Fox Aaron D, Chamberlain Adam, Frost Taeko, Cunningham Chinazo O

机构信息

a Department of Medicine , Albert Einstein College of Medicine , Bronx , New York , USA.

出版信息

Subst Abus. 2015;36(2):155-60. doi: 10.1080/08897077.2015.1011820.

DOI:10.1080/08897077.2015.1011820
PMID:25837290
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4706457/
Abstract

BACKGROUND

Harm reduction agencies complement addiction treatment by providing diverse services that improve the health of people who use drugs. Buprenorphine maintenance treatment (BMT) is an effective opioid addiction treatment that may be provided from flexible settings, potentially including harm reduction agencies. This study investigated attitudes toward different potential sites for BMT (harm reduction agencies, general medical clinics, and drug treatment programs) among harm reduction clients.

METHODS

Using computer-based interviews, participants indicated preferred potential site for BMT (harm reduction agency, drug treatment program, or general medical clinic), interest in BMT by potential site, motivation for treatment, and barriers to BMT. Multivariable logistic regression was used to determine factors associated with harm reduction agency preference.

RESULTS

Of 102 opioid users, the most preferred potential site for BMT was a harm reduction agency (51%), whereas fewer preferred general medical clinics (13%), drug treatment programs (12%), or were not interested in BMT (25%). In multivariable analysis, experiencing ≥1 barrier to BMT was strongly associated with preferring harm reduction agencies (adjusted odds ratio [aOR] = 3.39, 95% confidence interval [CI]: 1.00-11.43).

CONCLUSIONS

The potential to initiate BMT at harm reduction agencies is highly favorable among harm reduction clients, especially among those experiencing barriers to BMT. Offering BMT at harm reduction agencies could improve access to treatment, but studies are needed to determine safety and efficacy of this approach.

摘要

背景

减少伤害机构通过提供多种服务来补充成瘾治疗,这些服务可改善吸毒者的健康状况。丁丙诺啡维持治疗(BMT)是一种有效的阿片类药物成瘾治疗方法,可在灵活的场所提供,其中可能包括减少伤害机构。本研究调查了减少伤害服务对象对BMT不同潜在场所(减少伤害机构、普通医疗诊所和戒毒治疗项目)的态度。

方法

通过基于计算机的访谈,参与者表明BMT的首选潜在场所(减少伤害机构、戒毒治疗项目或普通医疗诊所)、对各潜在场所BMT的兴趣、治疗动机以及接受BMT的障碍。采用多变量逻辑回归确定与偏好减少伤害机构相关的因素。

结果

在102名阿片类药物使用者中,BMT的首选潜在场所是减少伤害机构(51%),而较少有人选择普通医疗诊所(13%)、戒毒治疗项目(12%)或对BMT不感兴趣(25%)。在多变量分析中,经历≥1个BMT障碍与更偏好减少伤害机构密切相关(调整后的优势比[aOR]=3.39,95%置信区间[CI]:1.00-11.43)。

结论

在减少伤害机构启动BMT的可能性在减少伤害服务对象中非常有利,尤其是在那些面临BMT障碍的人群中。在减少伤害机构提供BMT可以改善治疗的可及性,但需要进行研究以确定这种方法的安全性和有效性。