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口服和外用苯丙氨酸联合紫外线A照射治疗白癜风。

Vitiligo therapy with oral and topical phenylalanine with UVA exposure.

作者信息

Antoniou C, Schulpis H, Michas T, Katsambas A, Frajis N, Tsagaraki S, Stratigos J

机构信息

Dermatologic Clinic of Athens University, Andreas-Sygros Hospital, Greece.

出版信息

Int J Dermatol. 1989 Oct;28(8):545-7. doi: 10.1111/j.1365-4362.1989.tb04613.x.

DOI:10.1111/j.1365-4362.1989.tb04613.x
PMID:2583897
Abstract

The administration of phenylalanine (Phe) combined with UVA exposure was found to be effective in treating vitiligo. Twenty-one patients with vitiligo were divided in two groups: eleven patients were treated with oral L-Phe in a dose of 100 mg/kg body weight and with UVA exposure and ten patients were treated with oral L-Phe in a dose of 100 mg/kg body weight and with UVA exposure. In addition, in the second group, a cream containing 10% L-Phe was applied to the vitiliginous areas. The best results occurred in the second group. No side effects were found in either group.

摘要

研究发现,给予苯丙氨酸(Phe)并结合紫外线A(UVA)照射对治疗白癜风有效。21例白癜风患者被分为两组:11例患者接受口服L - Phe,剂量为100mg/kg体重,并结合UVA照射;10例患者同样接受口服L - Phe,剂量为100mg/kg体重,并结合UVA照射。此外,第二组患者在白癜风区域涂抹含10% L - Phe的乳膏。最佳疗效出现在第二组。两组均未发现副作用。

相似文献

1
Vitiligo therapy with oral and topical phenylalanine with UVA exposure.口服和外用苯丙氨酸联合紫外线A照射治疗白癜风。
Int J Dermatol. 1989 Oct;28(8):545-7. doi: 10.1111/j.1365-4362.1989.tb04613.x.
2
Oral and topical L-phenylalanine, clobetasol propionate, and UVA/sunlight--a new study for the treatment of vitiligo.口服及外用L-苯丙氨酸、丙酸氯倍他索和紫外线A/阳光——一项治疗白癜风的新研究。
J Drugs Dermatol. 2002 Sep;1(2):127-31.
3
Phenylalanine and UVA light for the treatment of vitiligo.苯丙氨酸与紫外线A光治疗白癜风。
Arch Dermatol Res. 1985;277(2):126-30. doi: 10.1007/BF00414110.
4
L-phenylalanine and UVA irradiation in the treatment of vitiligo.左旋苯丙氨酸与紫外线A照射治疗白癜风
Dermatology. 1994;188(3):215-8. doi: 10.1159/000247142.
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Vitiligo: a retrospective comparative analysis of treatment modalities in 500 patients.白癜风:500例患者治疗方式的回顾性比较分析
J Dermatol. 2001 Sep;28(9):461-6. doi: 10.1111/j.1346-8138.2001.tb00012.x.
6
[Repigmentation treatment of vitiligo with L-phenylalanine and UVA irradiation].[采用L-苯丙氨酸和紫外线A照射进行白癜风的色素再生治疗]
Z Hautkr. 1987 Apr 1;62(7):519-23.
7
[Treatment of vitiligo with phenylalanine and UV-A].用苯丙氨酸和紫外线A治疗白癜风
Hautarzt. 1993 Apr;44(4):208-9.
8
Phenylalanine with UVA for the treatment of vitiligo needs more testing for possible side effects.苯丙氨酸联合紫外线A治疗白癜风需要对可能的副作用进行更多测试。
J Am Acad Dermatol. 1999 Jun;40(6 Pt 1):1015. doi: 10.1016/s0190-9622(99)70100-3.
9
Oral phenylalanine loading and sunlight as source of UVA irradiation in vitiligo on the Caribbean island of Curacao NA.
J Trop Med Hyg. 1986 Jun;89(3):149-55.
10
Is the efficacy of psoralen plus ultraviolet A therapy for vitiligo enhanced by concurrent topical calcipotriol? A placebo-controlled double-blind study.补骨脂素加紫外线A疗法联合外用卡泊三醇治疗白癜风的疗效是否会增强?一项安慰剂对照双盲研究。
Br J Dermatol. 2001 Sep;145(3):472-5. doi: 10.1046/j.1365-2133.2001.04286.x.

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Nutrients. 2022 Jan 29;14(3):591. doi: 10.3390/nu14030591.
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Unconventional Treatments for Vitiligo: Are They (Un) Satisfactory?白癜风的非常规治疗方法:它们(不)令人满意吗?
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Guidelines for the treatment of vitiligo.
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