口服和外用苯丙氨酸联合紫外线A照射治疗白癜风。

Vitiligo therapy with oral and topical phenylalanine with UVA exposure.

作者信息

Antoniou C, Schulpis H, Michas T, Katsambas A, Frajis N, Tsagaraki S, Stratigos J

机构信息

Dermatologic Clinic of Athens University, Andreas-Sygros Hospital, Greece.

出版信息

Int J Dermatol. 1989 Oct;28(8):545-7. doi: 10.1111/j.1365-4362.1989.tb04613.x.

DOI:10.1111/j.1365-4362.1989.tb04613.x

PMID:2583897

Abstract

The administration of phenylalanine (Phe) combined with UVA exposure was found to be effective in treating vitiligo. Twenty-one patients with vitiligo were divided in two groups: eleven patients were treated with oral L-Phe in a dose of 100 mg/kg body weight and with UVA exposure and ten patients were treated with oral L-Phe in a dose of 100 mg/kg body weight and with UVA exposure. In addition, in the second group, a cream containing 10% L-Phe was applied to the vitiliginous areas. The best results occurred in the second group. No side effects were found in either group.

摘要

研究发现，给予苯丙氨酸（Phe）并结合紫外线A（UVA）照射对治疗白癜风有效。21例白癜风患者被分为两组：11例患者接受口服L - Phe，剂量为100mg/kg体重，并结合UVA照射；10例患者同样接受口服L - Phe，剂量为100mg/kg体重，并结合UVA照射。此外，第二组患者在白癜风区域涂抹含10% L - Phe的乳膏。最佳疗效出现在第二组。两组均未发现副作用。