Coelho Roberto Pinto, Biaggi Ricardo Helio, Jorge Rodrigo, Rodrigues Maria de Lourdes Veronese, Messias André
From the Department of Ophthalmology, Otorrinolaringology and Head and Neck Surgery, Medical School of Ribeirão Preto, University of São Paulo-Ribeirão Preto, São Paulo, Brazil.
From the Department of Ophthalmology, Otorrinolaringology and Head and Neck Surgery, Medical School of Ribeirão Preto, University of São Paulo-Ribeirão Preto, São Paulo, Brazil.
J Cataract Refract Surg. 2015 Apr;41(4):719-23. doi: 10.1016/j.jcrs.2014.06.040.
To compare the analgesic efficacy of 2 types of anesthetic techniques-topical and topical associated with cryoanalgesia-during cataract surgery.
Department of Ophthalmology, University of São Paulo, Ribeirão Preto, Brazil.
Prospective randomized study.
Patients with symmetrical bilateral cataract had phacoemulsification with the use of an intraocular irrigation solution at room temperature in 1 eye and a cold (4°C) solution in the contralateral eye (Group 2). The pain related to the procedure was assessed using a visual analog scale ranging from 0 to 100, with 0 representing no pain and 100 the worst pain. In addition, endothelial cell loss, the change in corneal thickness, and visual acuity were evaluated 30 days ± 2 (SD) after each surgery. The surgery duration, total irrigation volume, phacoemulsification time, and ultrasound power used were analyzed.
The study enrolled 25 patients (50 eyes). There was no statistically significant difference in the mean pain score between Group 1 (26.0 ± 3.7) and Group 2 (21.3 ± 3.6) (P = .2016, paired t test). No significant difference was found in the mean corneal endothelial cell loss (Group 1: 10.0% ± 0.4%; Group 2: 9.9% ± 0.3%; P = .7576), corneal thickness increase (Group 1: 1.5 ± 1.0 μm; Group 2: 1.4 ± 0.9 μm; P = .9340), or visual acuity gain (Group 1: 0.54 ± 0.06 logMAR; Group 2: 0.55 ± 0.09 logMAR; P = .8208).
There is no difference in the intensity of pain during phacoemulsification with the use of topical anesthesia or topical anesthesia associated with cryoanalgesia.
No author has a financial or proprietary interest in any material or method mentioned.
比较白内障手术中两种麻醉技术——表面麻醉和表面麻醉联合冷冻镇痛——的镇痛效果。
巴西圣保罗大学里贝朗普雷图分校眼科。
前瞻性随机研究。
双侧白内障对称的患者，一只眼睛使用室温的眼内冲洗液进行超声乳化手术，对侧眼睛使用冷（4°C）溶液（第2组）。使用0至100的视觉模拟量表评估与手术相关的疼痛，0表示无疼痛，100表示最剧烈疼痛。此外，在每次手术后30天±2（标准差）评估内皮细胞丢失、角膜厚度变化和视力。分析手术持续时间、总冲洗量、超声乳化时间和使用的超声功率。
该研究纳入了25名患者（50只眼）。第1组（26.0±3.7）和第2组（21.3±3.6）的平均疼痛评分之间无统计学显著差异（P = 0.2016，配对t检验）。在平均角膜内皮细胞丢失（第1组：10.0%±0.4%；第2组：9.9%±0.3%；P = 0.7576）、角膜厚度增加（第1组：1.5±1.0μm；第2组：1.4±0.9μm；P = 0.9340）或视力提高（第1组：0.54±0.06 logMAR；第2组：0.55±0.
