专题综述：儿童嗜酸性粒细胞性食管炎：对健康相关生活质量的影响及未来研究的潜在方向
Topical Review: Eosinophilic Esophagitis in Children: Implications for Health-Related Quality of Life and Potential Avenues for Future Research.
作者信息
Lynch Mary K, Avis Kristin T, Dimmitt Reed A, Goodin Burel R
机构信息
Department of Psychology and
Department of Pediatrics, University of Alabama at Birmingham.
出版信息
J Pediatr Psychol. 2015 Sep;40(8):727-32. doi: 10.1093/jpepsy/jsv032. Epub 2015 Apr 3.
Abstract
OBJECTIVE
To characterize the health-related quality of life (HRQoL) of children with eosinophilic esophagitis (EoE) as well as generate novel hypotheses for future research in this pediatric population.
METHOD
A literature review was completed using PubMed and the keywords below.
RESULTS
Research has shown that for children with EoE and their parents, symptom experiences and recommended treatments can have a negative impact on HRQoL. However, studies have yet to adequately address mechanisms that may help explain why this is. Areas of interest include sleep quality and disturbances, the experience of pain, and the presence of internalizing symptoms, all of which have the potential to uniquely and synergistically impact HRQoL.
CONCLUSION
With greater understanding of the associations among sleep, pain, internalizing symptoms, and HRQoL in children with EoE may come enhanced therapies that substantially improve the quality of their health care.
摘要
目的
描述嗜酸性食管炎（EoE）患儿的健康相关生活质量（HRQoL），并为该儿科人群的未来研究提出新的假设。
方法
使用PubMed及以下关键词完成文献综述。
结果
研究表明，对于EoE患儿及其父母，症状体验和推荐治疗可能会对HRQoL产生负面影响。然而，研究尚未充分探讨可能有助于解释其原因的机制。感兴趣的领域包括睡眠质量和干扰、疼痛体验以及内化症状的存在，所有这些都有可能对HRQoL产生独特且协同的影响。
结论
随着对EoE患儿睡眠、疼痛、内化症状和HRQoL之间关联的深入了解，可能会出现能显著改善其医疗保健质量的强化疗法。
相似文献
1
Topical Review: Eosinophilic Esophagitis in Children: Implications for Health-Related Quality of Life and Potential Avenues for Future Research.专题综述：儿童嗜酸性粒细胞性食管炎：对健康相关生活质量的影响及未来研究的潜在方向
J Pediatr Psychol. 2015 Sep;40(8):727-32. doi: 10.1093/jpepsy/jsv032. Epub 2015 Apr 3.
2
Disease-Related Predictors of Health-Related Quality of Life in Youth With Eosinophilic Esophagitis.特应性疾病相关预测因子对青少年嗜酸细胞性食管炎患者健康相关生活质量的影响。
J Pediatr Psychol. 2018 May 1;43(4):464-471. doi: 10.1093/jpepsy/jsx128.
3
Evidence of Disturbed Sleep in Children With Eosinophilic Esophagitis and Persistent Epigastric Pain.伴有嗜酸性粒细胞食管炎和持续性上腹痛的儿童睡眠紊乱的证据。
J Pediatr Psychol. 2018 Apr 1;43(3):331-341. doi: 10.1093/jpepsy/jsx117.
4
Health-Related Quality of Life and Costs Associated With Eosinophilic Esophagitis: A Systematic Review.健康相关生活质量与嗜酸性食管炎相关成本：系统评价。
Clin Gastroenterol Hepatol. 2018 Apr;16(4):495-503.e8. doi: 10.1016/j.cgh.2017.06.036. Epub 2017 Jun 24.
5
Systematic review: health-related quality of life in children and adults with eosinophilic oesophagitis-instruments for measurement and determinant factors.系统评价：嗜酸性粒细胞性食管炎患儿和成人的健康相关生活质量——测量工具和决定因素
Aliment Pharmacol Ther. 2017 Aug;46(4):401-409. doi: 10.1111/apt.14194. Epub 2017 Jun 22.
6
Symptom Burden and Quality of Life Over Time in Pediatric Eosinophilic Esophagitis.儿童嗜酸性食管炎随时间推移的症状负担和生活质量。
J Pediatr Gastroenterol Nutr. 2019 Dec;69(6):682-689. doi: 10.1097/MPG.0000000000002479.
7
Health-related quality of life over time in children with eosinophilic esophagitis and their families.嗜酸性粒细胞性食管炎患儿及其家庭随时间推移的健康相关生活质量
J Pediatr Gastroenterol Nutr. 2014 Sep;59(3):308-16. doi: 10.1097/MPG.0000000000000451.
8
Sleep, Anxiety, Somatization, Quality of Life, and Resilience in Pediatric Patients With Eosinophilic Esophagitis.儿童嗜酸性粒细胞性食管炎患者的睡眠、焦虑、躯体化、生活质量和韧性。
Clin Transl Gastroenterol. 2024 Mar 1;15(3):e00672. doi: 10.14309/ctg.0000000000000672.
9
Significance of feeding dysfunction in eosinophilic esophagitis.嗜酸性粒细胞性食管炎中喂养功能障碍的意义。
World J Gastroenterol. 2014 Aug 21;20(31):11019-22. doi: 10.3748/wjg.v20.i31.11019.
10
Pediatric Eosinophilic Esophagitis Symptom Scores (PEESS v2.0) identify histologic and molecular correlates of the key clinical features of disease.小儿嗜酸性粒细胞性食管炎症状评分（PEESS v2.0）可识别该疾病关键临床特征的组织学和分子学关联。
J Allergy Clin Immunol. 2015 Jun;135(6):1519-28.e8. doi: 10.1016/j.jaci.2015.03.004.
引用本文的文献
1
Assessment of the Severity and the Remission Criteria in Eosinophilic Esophagitis.嗜酸性食管炎严重程度及缓解标准的评估
Biomedicines. 2023 Dec 1;11(12):3204. doi: 10.3390/biomedicines11123204.
2
British Society of Gastroenterology (BSG) and British Society of Paediatric Gastroenterology, Hepatology and Nutrition (BSPGHAN) joint consensus guidelines on the diagnosis and management of eosinophilic oesophagitis in children and adults.英国胃肠病学会（BSG）和英国儿科胃肠病学、肝病学和营养学学会（BSPGHAN）联合制定的儿童和成人嗜酸性食管炎的诊断和管理共识指南。
Gut. 2022 Aug;71(8):1459-1487. doi: 10.1136/gutjnl-2022-327326. Epub 2022 May 23.
3
Measurement of Quality-of-Life Outcomes in Pediatric and Young Adult Patients Treated for Eosinophilic Esophagitis.接受嗜酸性粒细胞性食管炎治疗的儿科和青年患者生活质量结果的测量。
Cureus. 2022 Jan 27;14(1):e21675. doi: 10.7759/cureus.21675. eCollection 2022 Jan.
4
Sleep in children with eosinophilic esophagitis.嗜酸性粒细胞性食管炎患儿的睡眠情况。
World J Pediatr. 2021 Apr;17(2):111-114. doi: 10.1007/s12519-020-00408-7. Epub 2021 Feb 9.
5
Topical Steroids and Elimination Diets for EoE: Happier Together?用于嗜酸性食管炎的局部类固醇和排除饮食：携手共进会更美好？
Dig Dis Sci. 2018 Sep;63(9):2163-2164. doi: 10.1007/s10620-018-5055-y.
6
Disease-Related Predictors of Health-Related Quality of Life in Youth With Eosinophilic Esophagitis.特应性疾病相关预测因子对青少年嗜酸细胞性食管炎患者健康相关生活质量的影响。
J Pediatr Psychol. 2018 May 1;43(4):464-471. doi: 10.1093/jpepsy/jsx128.
7
Evidence of Disturbed Sleep in Children With Eosinophilic Esophagitis and Persistent Epigastric Pain.伴有嗜酸性粒细胞食管炎和持续性上腹痛的儿童睡眠紊乱的证据。
J Pediatr Psychol. 2018 Apr 1;43(3):331-341. doi: 10.1093/jpepsy/jsx117.
8
Eosinophilic esophagitis: search for noninvasive techniques for long-term monitoring.嗜酸性食管炎：寻找长期监测的非侵入性技术
Gastrointest Endosc. 2016 Feb;83(2):307-8. doi: 10.1016/j.gie.2015.07.006.
本文引用的文献
1
Health-related quality of life over time in children with eosinophilic esophagitis and their families.嗜酸性粒细胞性食管炎患儿及其家庭随时间推移的健康相关生活质量
J Pediatr Gastroenterol Nutr. 2014 Sep;59(3):308-16. doi: 10.1097/MPG.0000000000000451.
2
Eosinophilic esophagitis: clinical presentation in children.嗜酸性粒细胞性食管炎：儿童的临床表现
Gastroenterol Clin North Am. 2014 Jun;43(2):219-29. doi: 10.1016/j.gtc.2014.02.012.
3
The association of sleep and pain: an update and a path forward.睡眠与疼痛的关联：最新研究及未来方向
J Pain. 2013 Dec;14(12):1539-52. doi: 10.1016/j.jpain.2013.08.007.
4
Delay in diagnosis of eosinophilic esophagitis increases risk for stricture formation in a time-dependent manner.嗜酸粒细胞性食管炎的诊断延迟会使狭窄形成的风险呈时间依赖性增加。
Gastroenterology. 2013 Dec;145(6):1230-6.e1-2. doi: 10.1053/j.gastro.2013.08.015. Epub 2013 Aug 13.
5
Psychosocial dysfunction in children and adolescents with eosinophilic esophagitis.儿童和青少年嗜酸性食管炎的心理社会功能障碍。
J Pediatr Gastroenterol Nutr. 2013 Oct;57(4):500-5. doi: 10.1097/MPG.0b013e31829ce5ad.
6
ACG clinical guideline: Evidenced based approach to the diagnosis and management of esophageal eosinophilia and eosinophilic esophagitis (EoE).ACG 临床指南：食管嗜酸性粒细胞增多症和嗜酸性粒细胞性食管炎（EoE）的诊断和管理的循证方法。
Am J Gastroenterol. 2013 May;108(5):679-92; quiz 693. doi: 10.1038/ajg.2013.71. Epub 2013 Apr 9.
7
Impact of emotional and behavioral symptoms on quality of life in children and adolescents.情绪和行为症状对儿童和青少年生活质量的影响。
Qual Life Res. 2013 Mar;22(2):333-7. doi: 10.1007/s11136-012-0158-y. Epub 2012 Mar 23.
8
Behavioral functioning and treatment adherence in pediatric eosinophilic gastrointestinal disorders.儿科嗜酸性粒细胞性胃肠病的行为功能和治疗依从性。
Pediatr Allergy Immunol. 2012 Aug;23(5):494-9. doi: 10.1111/j.1399-3038.2012.01297.x. Epub 2012 Mar 22.
9
Pediatric and adult eosinophilic esophagitis: similarities and differences.小儿和成人嗜酸粒细胞性食管炎：相似与不同。
Allergy. 2012 Apr;67(4):477-90. doi: 10.1111/j.1398-9995.2012.02787.x. Epub 2012 Feb 8.
10
Eosinophilic esophagitis in children: frequency, clinical manifestations, endoscopic findings, and seasonal distribution.儿童嗜酸性食管炎：频率、临床表现、内镜表现和季节分布。
Adv Med Sci. 2011;56(2):151-7. doi: 10.2478/v10039-011-0038-7.
Zotero 插件