专题综述：儿童嗜酸性粒细胞性食管炎：对健康相关生活质量的影响及未来研究的潜在方向

Topical Review: Eosinophilic Esophagitis in Children: Implications for Health-Related Quality of Life and Potential Avenues for Future Research.

作者信息

Lynch Mary K, Avis Kristin T, Dimmitt Reed A, Goodin Burel R

机构信息

Department of Psychology and

Department of Pediatrics, University of Alabama at Birmingham.

出版信息

J Pediatr Psychol. 2015 Sep;40(8):727-32. doi: 10.1093/jpepsy/jsv032. Epub 2015 Apr 3.

DOI:10.1093/jpepsy/jsv032

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4553712/

Abstract

OBJECTIVE

To characterize the health-related quality of life (HRQoL) of children with eosinophilic esophagitis (EoE) as well as generate novel hypotheses for future research in this pediatric population.

METHOD

A literature review was completed using PubMed and the keywords below.

RESULTS

Research has shown that for children with EoE and their parents, symptom experiences and recommended treatments can have a negative impact on HRQoL. However, studies have yet to adequately address mechanisms that may help explain why this is. Areas of interest include sleep quality and disturbances, the experience of pain, and the presence of internalizing symptoms, all of which have the potential to uniquely and synergistically impact HRQoL.

CONCLUSION

With greater understanding of the associations among sleep, pain, internalizing symptoms, and HRQoL in children with EoE may come enhanced therapies that substantially improve the quality of their health care.

摘要

目的

描述嗜酸性食管炎（EoE）患儿的健康相关生活质量（HRQoL），并为该儿科人群的未来研究提出新的假设。

方法

使用PubMed及以下关键词完成文献综述。

结果

研究表明，对于EoE患儿及其父母，症状体验和推荐治疗可能会对HRQoL产生负面影响。然而，研究尚未充分探讨可能有助于解释其原因的机制。感兴趣的领域包括睡眠质量和干扰、疼痛体验以及内化症状的存在，所有这些都有可能对HRQoL产生独特且协同的影响。

结论

随着对EoE患儿睡眠、疼痛、内化症状和HRQoL之间关联的深入了解，可能会出现能显著改善其医疗保健质量的强化疗法。