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铒铬:钇钪镓石榴石激光治疗义齿相关创伤性溃疡的临床评估:一项随机对照临床研究。

Clinical evaluation of the Er,Cr:YSGG Laser therapy in the treatment of denture-related traumatic ulcerations: a randomized controlled clinical study.

作者信息

Kurtulmus-Yilmaz Sevcan, Yilmaz Hasan Guney, Tumer Hayriye, Sadettinoglu Koray

机构信息

1 Department of Prosthodontics, Faculty of Dentistry, Near East University , Mersin, Turkey .

出版信息

Photomed Laser Surg. 2015 Apr;33(4):224-9. doi: 10.1089/pho.2014.3846.

DOI:10.1089/pho.2014.3846
PMID:25844682
Abstract

OBJECTIVE

The aim of this study was to evaluate the efficacy of Er,Cr:YSGG laser irradiation in reducing pain and on healing rate of traumatic ulcerations (TU) during a 2-week period after placement of new complete dentures.

BACKGROUND DATA

Denture-related TU are painful, and result in patient discomfort. Lasers are used in the treatment of different kinds of mucosal lesions; however, there are no published data available concerning the clinical outcome of the use of laser therapy in the treatment of TU.

MATERIALS AND METHODS

Thirty edentulous patients with newly fabricated complete dentures who subsequently developed one or more pairs of TU participated in this study. For each patient, ulcerations were randomly assigned to the test and control groups. In the test group, ulcerations were irradiated with Er,Cr:YSGG laser. In the control group, the same laser without laser emission was used. Pain was assessed with a visual analog scale (VAS). Healing of ulcerations (HU) was graded by a clinician.

RESULTS

In the test group, laser irradiation provided significantly reduced pain immediately after treatment, and provided a significant healing effect 1 day after treatment, and these effects were maintained throughout the study. In the control group, baseline VAS scores were not statistically significant at baseline and 1 day after treatment, and HU scores were statistically significant 3, 7, and 14 days after treatment. Intergroup comparisons revealed that the differences in VAS and HU scores were statistically significant for all time periods after treatment, except for day 14.

CONCLUSIONS

Based on these findings, it may be concluded that Er,Cr:YSGG laser is effective in the treatment of TU.

摘要

目的

本研究旨在评估铒铬:钇-钪-镓-石榴石(Er,Cr:YSGG)激光照射在新全口义齿佩戴后2周内减轻创伤性溃疡(TU)疼痛及提高愈合率方面的疗效。

背景资料

义齿相关的TU会引起疼痛,给患者带来不适。激光被用于治疗多种黏膜病变;然而,关于激光疗法治疗TU的临床结果尚无公开数据。

材料与方法

30例佩戴新制作全口义齿后出现一对或多对TU的无牙颌患者参与了本研究。对于每位患者,溃疡随机分为试验组和对照组。试验组溃疡用Er,Cr:YSGG激光照射。对照组使用无激光发射的同一台激光。采用视觉模拟评分法(VAS)评估疼痛。由一名临床医生对溃疡愈合情况(HU)进行分级。

结果

试验组中,激光照射在治疗后即刻显著减轻疼痛,治疗后1天产生显著愈合效果,且这些效果在整个研究过程中持续存在。对照组中,基线VAS评分在基线时和治疗后1天无统计学意义,HU评分在治疗后3天、7天和14天有统计学意义。组间比较显示,除第14天外,治疗后所有时间段VAS和HU评分的差异均有统计学意义。

结论

基于这些发现,可以得出结论,Er,Cr:YSGG激光在治疗TU方面是有效的。

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