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儿童银屑病的最新进展。

Update on pediatric psoriasis.

作者信息

Silverberg Nanette B

机构信息

Department of Dermatology, 1090 Amsterdam Ave, Ste 11D, New York, NY 10025, USA.

出版信息

Cutis. 2015 Mar;95(3):147-52.

Abstract

Pediatric psoriasis accounts for approximately one-third of all cases of psoriasis. Although pediatric psoriasis was always understood to be a chronic inflammatory dermatosis, recent data suggest that pediatric psoriasis, similar to its adult equivalent, is part of a generalized inflammatory diathesis associated with metabolic syndrome, including obesity/overweight status, hypertriglyceridemia, high blood pressure, and insulin resistance. Given the recent proliferation of data demonstrating the generalized inflammatory nature of psoriasis, a new emphasis on adopting a healthier lifestyle and weight control as well as systemic therapies has emerged in the literature. This article briefly reviews selected studies published in the last 2 years that are pertinent to pediatric psoriasis.

摘要

儿童银屑病约占银屑病病例总数的三分之一。尽管儿童银屑病一直被认为是一种慢性炎症性皮肤病,但最近的数据表明,儿童银屑病与其成人形式相似,是一种与代谢综合征相关的全身性炎症素质的一部分,代谢综合征包括肥胖/超重状态、高甘油三酯血症、高血压和胰岛素抵抗。鉴于最近大量数据表明银屑病具有全身性炎症性质,文献中出现了对采用更健康的生活方式、控制体重以及进行全身治疗的新强调。本文简要回顾了过去两年发表的与儿童银屑病相关的部分研究。

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