Black Donald W, Coryell William, Crowe Raymond, McCormick Brett, Shaw Martha, Allen Jeff
Department of Psychiatry, University of Iowa Roy J. and Lucille A. Carver College of Medicine, Iowa City, Iowa.
Suicide Life Threat Behav. 2015 Dec;45(6):700-9. doi: 10.1111/sltb.12162. Epub 2015 Apr 6.
We examined the relationship between suicidal ideations and attempts in 95 probands with pathological gambling (PG), 91 controls, and 1075 first-degree relatives. The results were analyzed using logistic regression with generalized estimating equations. Thirty-four PG probands (35.8%) and 4 controls (4.4%) had attempted suicide (OR = 12.12, p < .001); in 13 probands, the attempt occurred before PG onset. Lifetime suicidal ideations occurred in 60 PG probands (63.2%) and 12 controls (13.2%) (OR = 11.29, p < .001). Suicidality in PG probands is a marker of PG severity and is associated with greater psychiatric comorbidity. Offspring of PG probands had significantly higher rates of suicide attempts than control offspring.
我们研究了95名病态赌博(PG)先证者、91名对照者以及1075名一级亲属的自杀意念与自杀未遂之间的关系。使用广义估计方程的逻辑回归分析结果。34名PG先证者(35.8%)和4名对照者(4.4%)有过自杀未遂经历(比值比[OR]=12.12,p<0.001);在13名先证者中,自杀未遂发生在PG发病之前。60名PG先证者(63.2%)和12名对照者(13.2%)有过终生自杀意念(OR=11.29,p<0.001)。PG先证者的自杀倾向是PG严重程度的一个标志,并且与更多的精神疾病共病相关。PG先证者的后代自杀未遂率显著高于对照者的后代。