Liu Jing, Yan Fang, Ma Xin, Guo Hong-Li, Tang Yi-Lang, Rakofsky Jeffrey J, Wu Xiao-Mei, Li Xiao-Qiang, Zhu Hong, Guo Xiao-Bing, Yang Yang, Li Peng, Cao Xin-Dong, Li Hai-Ying, Li Zhen-Bo, Wang Ping, Xu Qiu-Yue
Beijing Anding Hospital, Capital Medical University, Beijing, China.
Beijing Anding Hospital, Capital Medical University, Beijing, China.
J Affect Disord. 2015 Jul 1;179:74-81. doi: 10.1016/j.jad.2015.03.009. Epub 2015 Mar 14.
Major depressive disorder (MDD) is the most prevalent mental disorder in the general population and has been associated with socioeconomic factors. Beijing has undergone significant socioeconomic changes in last decade, however no large-scale community epidemiological surveys of MDD have been conducted in Beijing since 2003.
To determine the prevalence of MDD and its socio-demographic correlates in a representative household sample of the general population in Beijing, China.
Data were collected from the 2010 representative household epidemiological survey of mental disorders in Beijing. The multistage cluster random sampling method was used to select qualified subjects in 18 districts and counties, and then face-to-face interviews were administered using the Chinese version of Structured Clinical Interview for DSM-IV-TR Axis I Disorders-Patient Edition (SCID-I/P) during November 1, 2010 to December 31, 2010.
19,874 registered permanent residents were randomly identified and 16,032 (response rate=80.7%) completed face-to-face interviews. The time-point and life-time prevalence rates of MDD were estimated to be 1.10% (95% CI: 0.94-1.26%) and 3.56% (95% CI: 3.27-3.85%) respectively. Significant differences were found in sex, age, location of residence, marital status, education, employment status, personal/family monthly income, perception of family environment and relationship with others, when comparing residents with MDD to those without MDD. Those who were female, aged 45 or above, reported low family income, or reported an "average" or "poor" family environment were associated with a higher risk of MDD.
The prevalence of MDD reported in this survey is relatively lower than that in other western countries. Female sex, age older than 45, low family income, and poor family environment appear to be independent risk factors for MDD.
重度抑郁症(MDD)是普通人群中最常见的精神障碍,且与社会经济因素相关。北京在过去十年经历了重大的社会经济变革,然而自2003年以来,北京尚未进行过大规模的社区抑郁症流行病学调查。
确定中国北京普通人群中有代表性的家庭样本中重度抑郁症的患病率及其社会人口学相关因素。
数据收集自2010年北京有代表性的家庭精神障碍流行病学调查。采用多阶段整群随机抽样方法在18个区县选取合格受试者,然后于2010年11月1日至2010年12月31日期间使用中文版《美国精神障碍诊断与统计手册第四版修订版轴I障碍结构化临床访谈-患者版》(SCID-I/P)进行面对面访谈。
随机确定了19874名登记常住人口,16032人(应答率=80.7%)完成了面对面访谈。重度抑郁症的时间点患病率和终生患病率估计分别为1.10%(95%可信区间:0.94 - 1.26%)和3.56%(95%可信区间:3.27 - 3.85%)。将患有重度抑郁症的居民与未患重度抑郁症的居民进行比较时,发现性别、年龄、居住地点、婚姻状况、教育程度、就业状况、个人/家庭月收入、对家庭环境的认知以及与他人的关系存在显著差异。女性、45岁及以上、家庭收入低或报告家庭环境为“一般”或“差”的人群患重度抑郁症的风险较高。
本次调查中报告的重度抑郁症患病率相对低于其他西方国家。女性、45岁以上、家庭收入低和家庭环境差似乎是重度抑郁症的独立危险因素。