L'Azou Maïna, Jean-Marie Janick, Bessaud Maël, Cabié André, Césaire Raymond, de Lamballerie Xavier, Courbil Rémi, Richard Pascale
Am J Trop Med Hyg. 2015 Jun;92(6):1137-1140. doi: 10.4269/ajtmh.14-0211. Epub 2015 Apr 6.
Using an anti-dengue immunoglobulin G (IgG) indirect enzyme-linked immunosorbent assay, seroprevalence was determined among 783 adult blood donors in the French Caribbean islands of Guadeloupe and Martinique in 2011. Overall, 93.5% [91.5; 95.1] samples were positive for dengue antibodies, 90.7% (350 of 386) in Martinique and 96.2% (382 of 397) in Guadeloupe. Only 30% of these adults recalled having had dengue disease before. Serotype-specific neutralization assays applied to a subset of IgG-positive samples indicated that a majority (77 of 96; 80%) reacted to the four serotypes. These seroprevalence findings are the first reported for Guadeloupe and Martinique and are consistent with the dengue epidemiology in these territories.
2011年，在法属加勒比岛屿瓜德罗普岛和马提尼克岛，采用抗登革热免疫球蛋白G（IgG）间接酶联免疫吸附测定法，对783名成年献血者进行了血清流行率检测。总体而言，93.5%[91.5；95.1]的样本登革热抗体呈阳性，马提尼克岛为90.7%（386例中的350例），瓜德罗普岛为96.2%（397例中的382例）。这些成年人中只有30%回忆起曾患过登革热。对一部分IgG阳性样本进行的血清型特异性中和试验表明，大多数（96例中的77例；80%）对四种血清型有反应。这些血清流行率调查结果是瓜德罗普岛和马提尼克岛首次报告的，与这些地区的登革热流行病学情况相符。
