Pavlidis Antonis N, Jones Daniel A, Sirker Alex, Mathur Anthony, Smith Elliot J
Department of Cardiology, London Chest Hospital, Barts Health NHS Trust, London, UK.
Curr Cardiol Rev. 2016;12(1):12-7. doi: 10.2174/1573403x11666150407110849.
The field of percutaneous intervention for chronic total occlusion (CTO) has enjoyed significant innovations in the recent years. Novel techniques and technologies have revolutionized the field and have resulted in considerably higher success rates even in patients with high anatomical complexity. Successful CTO recanalization is associated with significant clinical benefits, such as the improvement of angina and quality of life, reduced rates of surgical revascularization, improvement of left ventricular function and decreased mortality rates. However, complex CTO procedures often require prolonged x-ray exposure which have been associated with adverse long term outcomes.
近年来,慢性完全闭塞病变(CTO)的经皮介入治疗领域取得了重大创新。新技术和工艺彻底改变了这一领域,即使在解剖结构复杂的患者中也取得了显著更高的成功率。成功的CTO再通与显著的临床益处相关,如心绞痛改善和生活质量提高、外科血运重建率降低、左心室功能改善以及死亡率降低。然而,复杂的CTO手术通常需要长时间的X线照射,这与不良的长期预后相关。