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经皮冠状动脉介入治疗和冠状动脉造影期间与更高辐射暴露相关的临床和操作特征。

Clinical and procedural characteristics associated with higher radiation exposure during percutaneous coronary interventions and coronary angiography.

机构信息

Department of Cardiology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.

出版信息

Circ Cardiovasc Interv. 2013 Oct 1;6(5):501-6. doi: 10.1161/CIRCINTERVENTIONS.113.000220. Epub 2013 Sep 24.

Abstract

BACKGROUND

We aim to study the clinical and procedural characteristics associated with higher radiation exposure in patients undergoing percutaneous coronary interventions (PCIs) and coronary angiography.

METHODS AND RESULTS

Our present study included all coronary angiography and PCI procedures in 5 PCI centers in the Western part of Sweden, between January 1, 2008, and January 19, 2012. The radiation exposure and clinical data were collected prospectively in these 5 PCI centers in Sweden as part of the Swedish Coronary Angiography and Angioplasty Registry (SCAAR). A prediction model was made for the radiation exposure (dose-area product) expressed in Gy·cm(2). A total of 20 669 procedures were included in the present study, consisting of 9850 PCI and 10 819 coronary angiography procedures. In multivariable analyses, body mass index (β=1.04; confidence interval [CI], 1.04-1.04; P<0.001); history of coronary artery bypass graft surgery (β=1.32; CI, 1.28-1.32; P<0.001); 2, 3, or 4 treated lesions (2 treated lesions: β=1.95; CI, 1.84-2.03; P<0.001; 3 treated lesions: β=2.34; CI, 2.16-2.53; P<0.001; and 4 treated lesions: β=2.83; CI, 2.53-3.16; P<0.001); and chronic total occlusion lesions (β=1.39; CI, 1.31-1.48; P<0.001) were associated with the highest radiation exposure. After adjusting for procedural complexity, radial access route was not associated with increased radiation exposure (β=1.00; CI, 0.98-1.03; P=0.67).

CONCLUSIONS

In the largest study population to assess radiation exposure, we found that high body mass index, history of coronary artery bypass graft surgery, number of treated lesions, and chronic total occlusions were associated with the highest patient radiation exposure. Radial access site was not associated with higher radiation exposure when compared with femoral approach.

摘要

背景

我们旨在研究接受经皮冠状动脉介入治疗(PCI)和冠状动脉造影的患者中与较高辐射暴露相关的临床和程序特征。

方法和结果

我们的研究包括 2008 年 1 月 1 日至 2012 年 1 月 19 日期间瑞典西部 5 个 PCI 中心的所有冠状动脉造影和 PCI 手术。瑞典冠状动脉造影和血管成形术登记处(SCAAR)的这些瑞典 5 个 PCI 中心前瞻性地收集了辐射暴露和临床数据。制作了一个用于表示(剂量-面积乘积)的辐射暴露预测模型。共有 20669 例手术纳入本研究,包括 9850 例 PCI 和 10819 例冠状动脉造影。在多变量分析中,体重指数(β=1.04;置信区间[CI],1.04-1.04;P<0.001);冠状动脉旁路移植术史(β=1.32;CI,1.28-1.32;P<0.001);治疗 2、3 或 4 个病变(治疗 2 个病变:β=1.95;CI,1.84-2.03;P<0.001;治疗 3 个病变:β=2.34;CI,2.16-2.53;P<0.001;治疗 4 个病变:β=2.83;CI,2.53-3.16;P<0.001);慢性完全闭塞病变(β=1.39;CI,1.31-1.48;P<0.001)与最高的辐射暴露相关。在调整了手术复杂性后,桡动脉入路与增加的辐射暴露无关(β=1.00;CI,0.98-1.03;P=0.67)。

结论

在评估辐射暴露的最大研究人群中,我们发现高体重指数、冠状动脉旁路移植术史、治疗病变数量和慢性完全闭塞与患者最高的辐射暴露相关。与股动脉入路相比,桡动脉入路与更高的辐射暴露无关。

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