社交感知中的灵长类杏仁核——来自电生理记录与刺激的见解
The primate amygdala in social perception - insights from electrophysiological recordings and stimulation.
作者信息
Rutishauser Ueli, Mamelak Adam N, Adolphs Ralph
机构信息
Department of Neurosurgery, Cedars-Sinai Medical Center, Los Angeles, CA, USA; Department of Neurology, Cedars-Sinai Medical Center, Los Angeles, CA, USA; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, USA; Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
Department of Neurosurgery, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
出版信息
Trends Neurosci. 2015 May;38(5):295-306. doi: 10.1016/j.tins.2015.03.001. Epub 2015 Apr 3.
The role of the amygdala in emotion and social perception has been intensively investigated primarily through studies using functional magnetic resonance imaging (fMRI). Recently, this topic has been examined using single-unit recordings in both humans and monkeys, with a focus on face processing. The findings provide novel insights, including several surprises: amygdala neurons have very long response latencies, show highly nonlinear responses to whole faces, and can be exquisitely selective for very specific parts of faces such as the eyes. In humans, the responses of amygdala neurons correlate with internal states evoked by faces, rather than with their objective features. Current and future studies extend the investigations to psychiatric illnesses such as autism, in which atypical face processing is a hallmark of social dysfunction.
杏仁核在情绪和社会认知中的作用主要通过使用功能磁共振成像（fMRI）的研究进行了深入调查。最近，这个主题已经通过对人类和猴子的单神经元记录进行了研究，重点是面部处理。这些发现提供了新的见解，包括几个令人惊讶的地方：杏仁核神经元具有非常长的反应潜伏期，对整个面部表现出高度非线性反应，并且可以对面部的非常特定部分（如眼睛）具有极高的选择性。在人类中，杏仁核神经元的反应与面部引发的内部状态相关，而不是与它们的客观特征相关。当前和未来的研究将调查扩展到诸如自闭症等精神疾病，其中非典型面部处理是社会功能障碍的一个标志。
Zotero 插件