Gahleitner Florian, Legg Julian, Holland Emma, Pearson Sarah, Roberts Graham
NIHR Respiratory Biomedical Research Unit, University Hospitals of Southampton, NHS Foundation Trust, Southampton, UK.
Clinical and Experimental Sciences and Human Development in Health Academic Units, Faculty of Medicine, University of Southampton, Southampton, UK.
Pediatr Pulmonol. 2016 Jan;51(1):5-12. doi: 10.1002/ppul.23200. Epub 2015 Apr 2.
A meaningful analysis in research requires robust, valid data. Paper diaries allow the collection of data from individuals over time but are notorious for poor compliance and validity. SMS-technology is a novel method for data collection in medical research. Time-tagged SMS are transferred directly to an electronic file. We used SMS to collect symptoms and peak flow rate (PEFR) meter readings from 32 children with asthma. Parents responded first to five SMS daily for 7 days during an asymptomatic period and then for 14 days during a cold. Compliance with use of PEFR meter and SMS system were assessed. Digital PEFR meters enabled data download at the end of the study to confirm validity of transmitted data. Parents of 24 participants provided feedback about this data collection tool. Mean (±SD) "SMS-diary and PEFR-meter compliance" were 96% (±8) and 84% (±21) during baseline and 91% (±12) and 82% (±20) during cold respectively. Correctly reported PEFR values were found in 65.5% of all cases, in 8.3% PEFR values sent were "self-invented" and 2.4% of values were missing. All of the 22 parents completing the baseline questionnaire were happy to use SMS for this study. Of the 20 parents completing the follow up questionnaire, 95% (19/20) found the system user-friendly, 55% (11/20) would be more likely to participate in studies if they were using SMS data collection and 25% (5/20) were "sometimes unhappy" about receiving messages. This real-time capture of data is well accepted and could avoid some of the pitfalls of backfilled paper diaries.
研究中的有意义分析需要可靠、有效的数据。纸质日记可以随时间收集个体数据，但因依从性差和有效性低而声名狼藉。短信技术是医学研究中一种新型的数据收集方法。带时间标记的短信会直接传输到电子文件中。我们使用短信从32名哮喘儿童中收集症状和呼气峰值流速（PEFR）仪读数。在无症状期，家长们连续7天每天回复5条短信，然后在感冒期间回复14天。评估了PEFR仪和短信系统的使用依从性。数字PEFR仪在研究结束时能够下载数据，以确认传输数据的有效性。24名参与者的家长对这种数据收集工具提供了反馈。在基线期，“短信日记和PEFR仪的依从性”平均（±标准差）分别为96%（±8）和84%（±21），在感冒期间分别为91%（±12）和82%（±20）。在所有病例中，65.5%的PEFR值报告正确，8.3%发送的PEFR值是“自行编造的”，2.4%的值缺失。完成基线调查问卷的22位家长都乐意在本研究中使用短信。在完成随访调查问卷的20位家长中，95%（19/20）认为该系统用户友好，55%（11/20）表示如果使用短信数据收集，他们更有可能参与研究，25%（5/20）对收到短信“有时会不高兴”。这种数据的实时采集很容易被接受，并且可以避免回填纸质日记的一些缺陷。
