中国吉氏巴贝斯虫引起的犬巴贝斯虫病：一种分子方法
Canine Babesiosis in China Caused by Babesia gibsoni: A Molecular Approach.
作者信息
Yao Da-Wei, Jiang Jing-Ya, Yu Ze-Zhong, Yao Dong-Qin, Yang De-Ji, ZhAO Yan-Bing
机构信息
College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, Jiangsu, China.
YuXi Agriculture Vocation-Technical College, Yuxi, Yunnan, China.
出版信息
Iran J Parasitol. 2014 Apr-Jun;9(2):163-8.
BACKGROUND
To provide a point of reference to study the epidemiology and clinical expression of canine babesiosis in China.
METHODS
A total of 30 dogs infected with canine babesiosis were evaluated by mean of clinical history, physical examination, hematological, restriction fragment length polymorphism of PCR products (PCR-RFLP) and sequencing analysis.
RESULT
The most prevalent clinical abnormalities were lethargy (100%), anorexia (100%), pale or icteric mucous membranes (80%), fever (70%) and dark urine (70%). Hematology parameters revealed that anemia and thrombocytopenia were the major abnormalities in blood of dogs infected with canine babesia. The results of PCR-RFLP and sequencing analysis indicated that B. gibsoni was the main species responsible for canine babesiosis cases at the time of the study in Nanjing, China.
CONCLUSIONS
The results provide valuable information for better understanding of the epidemiology of canine babesiosis in China.
背景
为研究中国犬巴贝斯虫病的流行病学和临床表现提供参考依据。
方法
通过临床病史、体格检查、血液学检查、聚合酶链反应产物的限制性片段长度多态性分析（PCR-RFLP）和测序分析，对30只感染犬巴贝斯虫病的犬进行评估。
结果
最常见的临床异常表现为嗜睡（100%）、厌食（100%）、黏膜苍白或黄疸（80%）、发热（70%）和尿液颜色加深（70%）。血液学参数显示，贫血和血小板减少是感染犬巴贝斯虫的犬血液中的主要异常表现。PCR-RFLP和测序分析结果表明，在中国南京进行本研究时，吉氏巴贝斯虫是导致犬巴贝斯虫病病例的主要虫种。
结论
这些结果为更好地了解中国犬巴贝斯虫病的流行病学提供了有价值的信息。
Zotero 插件