Nicolaides A R, Rhys Evans P, Fisher C
Department of Pathology, Royal Marsden Hospital, London.
J Laryngol Otol. 1989 Oct;103(10):978-9. doi: 10.1017/s0022215100110680.
A case of adenosquamous carcinoma of the thyroid gland is presented. This rare form of cancer behaves in an aggressive manner similar to anaplastic carcinoma and is characterized histologically by the intimate blending of the squamous and glandular elements. The prognostic significance of identifying areas of malignant squamous epithelium within papillary carcinoma as opposed to the much more common benign squamous metaplasia, is highlighted. The pathogenesis, differential diagnosis and management of the condition are discussed.
本文报告一例甲状腺腺鳞癌。这种罕见的癌症表现出与未分化癌相似的侵袭性，组织学特征为鳞状和腺性成分紧密融合。强调了鉴别乳头状癌内恶性鳞状上皮区域与更为常见的良性鳞状化生的预后意义。并讨论了该疾病的发病机制、鉴别诊断和治疗。
