Jacob B, Heller C, Daldrup T, Bürrig K F, Barz J, Bonte W
Department of Forensic Medicine, Heinrich-Heine-University, Düsseldorf, West Germany.
J Forensic Sci. 1989 Nov;34(6):1408-12.
Among reported cases of abuse of volatile anesthetics there is only one of enflurane intoxication. We report another fatal enflurane intoxication. A 21-year-old man found dead seemed to have experimented with enflurane. Three and one-half days after death high amounts of enflurane were detected in blood, brain, and subcutaneous fat. Gas chromatographic quantification revealed the following high enflurane concentrations: blood: 130 mg/l-1, brain: 350 mg/l-1, and subcutaneous fat: 100 mg/l-1. Histologic signs of drug-induced damage were lacking. No suicide intentions became known. It was concluded that the young man died of an accidental intoxication while abusing enflurane.
在已报道的挥发性麻醉剂滥用病例中,只有一例是安氟醚中毒。我们报告另一例致命的安氟醚中毒病例。一名被发现死亡的21岁男子似乎曾尝试使用安氟醚。死后三天半,在血液、大脑和皮下脂肪中检测到大量安氟醚。气相色谱定量分析显示安氟醚浓度很高:血液:130毫克/升-1,大脑:350毫克/升-1,皮下脂肪:100毫克/升-1。缺乏药物引起损伤的组织学迹象。未发现自杀意图。结论是该年轻人在滥用安氟醚时死于意外中毒。