Li Zhi-Qun, LingHu En-Qiang, Hu Min, Li Wei-Min, Huang Qi-Yang, Zhao Yong-Wei
Zhi-Qun Li, En-Qiang LingHu, Qi-Yang Huang, Yong-Wei Zhao, Department of Hepatology and Gastroenterology, Chinese PLA General Hospital, Beijing 100853, China.
World J Gastroenterol. 2015 Apr 7;21(13):3888-92. doi: 10.3748/wjg.v21.i13.3888.
To explore the effect of in vitro porcine esophageal variceal pressure on complete ligation degree for polycyclic ligators.
An in vitro model of experimental porcine venous vessels was used to test various venous pressures. Three treatment groups were designated according to the preset pressure range: P1 = 25-30 cmH₂O; P₂ = 35-40 cmH₂O; P₃ = 45-50 cmH2O. The effect of pressure on ligation was assessed and compared among the groups.
Complete ligation was achieved at a rate of 56.25% (18/32) in group P1, 37.5% (12/32) in group P₂, and 33.33% (11/33) in group P₃ (χ (2) = 3.6126; P = 0.0573).
Higher variceal pressures impair the ligation completion rate. Therefore, measuring variceal pressure may help predict the effect of endoscopic ligation and guide treatment choice.
探讨体外猪食管静脉曲张压力对多环结扎器完全结扎程度的影响。
采用体外实验猪静脉血管模型测试不同静脉压力。根据预设压力范围分为三个治疗组:P1 = 25 - 30 cmH₂O;P₂ = 35 - 40 cmH₂O;P₃ = 45 - 50 cmH₂O。评估并比较各组压力对结扎的影响。
P1组完全结扎率为56.25%(18/32),P₂组为37.5%(12/32),P₃组为33.33%(11/33)(χ² = 3.6126;P = 0.0573)。
较高的静脉曲张压力会损害结扎完成率。因此,测量静脉曲张压力可能有助于预测内镜结扎效果并指导治疗选择。