Chaudhari L S, Naik S, Kamath S K, Bhatt M M
J Postgrad Med. 1989 Jan;35(1):9-13.
The use of atropine sulphate in the paediatric age group as a premedicant orally in a dosage of 0.02 mg/kg body weight 70 minutes prior to surgery was found to be as effective as atropine sulphate given intramuscularly 35 minutes prior to surgery in a dosage of 0.01 mg/kg body weight. This avoids the unpleasant memory of needle prick; The duration of effect as studied in the normal healthy children not subjected to surgery was found to be 2 1/2-3 hours.
在儿科年龄组中,术前70分钟口服硫酸阿托品作为术前用药,剂量为0.02毫克/千克体重,被发现与术前35分钟肌肉注射硫酸阿托品,剂量为0.01毫克/千克体重一样有效。这避免了针刺带来的不愉快记忆;在未接受手术的正常健康儿童中研究发现,其作用持续时间为2.5至3小时。