Kopp Sigmar, Warkentin Mareike, Öri Ferenc, Ottl Peter, Kundt Günther, Frerich Bernhard
Niklotstrasse 39, 18273 G ü strow, Germany.
Biomed Tech (Berl). 2012 Oct;57(5):365-70. doi: 10.1515/bmt-2012-0015.
This study was designed to determine and statistically analyze bone-to-implant contact (BIC) values for human specimens segmented in at least two different locations.
Samples of human bone with fractured osseointegrated implants were obtained from six patients. Sections were prepared, dehydrated, and resin infiltrated. Undecalcified bone sections were produced using the thin-section technique according to Donath, ultimately obtaining a section thickness of approximately 20 μm. Fifteen specimens were available for histomorphometry. The bone sections were digitized and analyzed. The bone-to-metal contact (BMC) parameter was determined histomorphometrically. The BMC was returned in terms of the visibly bone-covered implant surfaces as a percentage of the total implant surface shown.
The values obtained for the six implants were arranged as six maximum-distance pairs and tested for significance using the t-test for dependent samples. The mean difference in BIC was 11.69±9.79%. The two-sided test showed a significant difference (p=0.033).
The accidental or deliberate choice of section plane for a bone-implant block has an influence on the BIC value. To make BIC values more comparable, a standardization of section planes is desirable.
本研究旨在确定并统计分析在至少两个不同位置分割的人体标本的骨与种植体接触（BIC）值。
从6名患者身上获取带有骨折的骨结合种植体的人体骨样本。制备切片，进行脱水和树脂浸润。根据多纳特的薄切片技术制作不脱钙骨切片，最终获得厚度约为20μm的切片。有15个标本可用于组织形态计量学分析。对骨切片进行数字化处理和分析。通过组织形态计量学确定骨与金属接触（BMC）参数。BMC以可见骨覆盖的种植体表面占所示种植体总表面的百分比表示。
将6个种植体获得的值排列为6对最大距离对，并使用配对样本t检验进行显著性检验。BIC的平均差异为11.69±9.79%。双侧检验显示差异有统计学意义（p = 0.033）。
骨-种植体块切片平面的偶然或有意选择会影响BIC值。为使BIC值更具可比性，需要对切片平面进行标准化。
