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飞秒激光设置对近视小切口透镜切除术术后视觉性能的影响。

Effect of femtosecond laser setting on visual performance after small-incision lenticule extraction for myopia.

作者信息

Kamiya Kazutaka, Shimizu Kimiya, Igarashi Akihito, Kobashi Hidenaga

机构信息

Department of Ophthalmology, University of Kitasato School of Medicine, Kanagawa, Japan.

出版信息

Br J Ophthalmol. 2015 Oct;99(10):1381-7. doi: 10.1136/bjophthalmol-2015-306717. Epub 2015 Apr 8.

Abstract

AIM

To compare the effect of the two femtosecond laser settings on visual performance after small-incision lenticule extraction (SMILE) for myopia and myopic astigmatism.

METHODS

Forty-four eyes of 22 consecutive patients who underwent SMILE with an energy level of 140 nJ (spot distance 3.0 µm) in one eye, and with an energy level of 170 nJ (spot distance 4.5 µm) in the other eye, the eyes being randomly assigned. Preoperatively, 1 week, and 1 and 3 months postoperatively, the values of the modulation transfer function (MTF) cutoff frequency, Strehl ratio, objective scattering index (OSI) and Optical Quality Analysis System (OQAS) values (OVs) for these eyes were quantitatively assessed using an Optical Quality Analysis System (Visiometrics).

RESULTS

No significant differences were detected between the two groups in the visual and refractive outcomes, or in the MTF cutoff frequency, the Strehl ratio, the OSI, the OV 100%, the OV 20% or the OV 9% at any time point before or after surgery.

CONCLUSIONS

SMILE with energy settings of 140 and 170 nJ was effective for the correction of myopia and myopic astigmatism. It is indicated that the differences in laser setting (140 nJ, spot distance 3.0 µm vs 170 nJ, spot distance 4.5 µm) did not significantly affect the optical quality including the intraocular scattering of eyes undergoing SMILE.

CLINICAL TRIAL NUMBER

The protocol was registered with University Hospital Medical Information Network Clinical Trial Registry (UMIN000016241).

摘要

目的

比较两种飞秒激光参数设置在小切口透镜切除术(SMILE)治疗近视及近视散光后对视觉性能的影响。

方法

连续22例患者的44只眼接受了SMILE手术,其中一只眼采用能量水平为140 nJ(光斑间距3.0 µm),另一只眼采用能量水平为170 nJ(光斑间距4.5 µm),双眼随机分配。术前、术后1周、1个月和3个月,使用光学质量分析系统(Visiometrics)对这些眼睛的调制传递函数(MTF)截止频率、斯特列尔比、客观散射指数(OSI)和光学质量分析系统(OQAS)值(OVs)进行定量评估。

结果

两组在视觉和屈光结果方面,以及在手术前后的任何时间点,MTF截止频率、斯特列尔比、OSI、OV 100%、OV 20%或OV 9%均未检测到显著差异。

结论

能量设置为140和170 nJ的SMILE手术对近视和近视散光的矫正有效。结果表明,激光设置的差异(140 nJ,光斑间距3.0 µm与170 nJ,光斑间距4.5 µm)并未显著影响接受SMILE手术眼睛的光学质量,包括眼内散射。

临床试验编号

该方案已在大学医院医学信息网络临床试验注册中心(UMIN000016241)注册。

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