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埃及开罗轮状病毒相关急性婴儿腹泻的流行病学和临床特征

Epidemiological and clinical features of rotavirus associated acute infantile diarrhoea in Cairo, Egypt.

作者信息

el-Mougi M, Amer A, el-Abhar A, Hughes J, el-Shafie A

出版信息

J Trop Pediatr. 1989 Oct;35(5):230-3. doi: 10.1093/tropej/35.5.230.

DOI:10.1093/tropej/35.5.230
PMID:2585579
Abstract

Rotavirus was looked for in stool specimens from 200 randomly chosen infants and children aged 1-24 months presenting with acute diarrhoea of not more than 5 days duration at the Bab El-Sha'reya University Hospital during a 12-month period (January-December 1986). Forty per cent of cases were positive for rotavirus by the ELISA technique. Considering the seasonal pattern, during the hot months May to August, the monthly percentage of rotavirus positive cases ranged from 24 to 32 per cent while during the rest of the year, the range was from 37 to 60 per cent. There was no statistically significant difference between the rotavirus positive and negative cases as regards mean age in months (9.5 +/- 5.1 and 9.2 +/- 5.5, respectively), type of feeding or nutritional status. However, rotavirus positive cases were significantly more likely to present earlier, to have watery stools, to vomit or even to have vomiting before the onset of diarrhoea and to have respiratory symptoms. On the other hand, the means of dehydration score, rectal temperature and serum Na+ were not significantly different between the two groups.

摘要

在12个月期间(1986年1月至12月),从Bab El-Sha'reya大学医院随机选取200名1至24个月出现急性腹泻且病程不超过5天的婴幼儿粪便样本中检测轮状病毒。采用酶联免疫吸附测定(ELISA)技术,40%的病例轮状病毒呈阳性。考虑到季节模式,在炎热的5月至8月期间,轮状病毒阳性病例的月度百分比在24%至32%之间,而在一年中的其他时间,该范围为37%至60%。轮状病毒阳性和阴性病例在平均月龄(分别为9.5±5.1和9.2±5.5)、喂养方式或营养状况方面无统计学显著差异。然而,轮状病毒阳性病例更有可能发病较早、出现水样便、呕吐,甚至在腹泻发作前就呕吐,并且出现呼吸道症状。另一方面,两组之间的脱水评分、直肠温度和血清钠均值无显著差异。

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